20 citations
,
September 2019 in “Journal of Cosmetic Dermatology” This study found that combining stromal vascular fraction with PRP injections significantly improved hair density and reduced hair loss more effectively than PRP alone in patients with androgenetic alopecia.
20 citations
,
July 2019 in “Stem cell investigation” This study found that the combination of stromal vascular fraction and platelet-rich plasma accelerated wound healing in rats more effectively than either treatment alone or saline.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.
20 citations
,
February 2017 in “International Journal of Dermatology” This review highlights recent findings on blood-derived autologous therapies for skin repair and wound healing but presents no new clinical results, emphasizing future challenges and prospects in regenerative dermatology.
20 citations
,
September 2016 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma treatment significantly increased hair diameter and density, stopped hair fall, and boosted hair growth in men with hair loss, with no reported side effects.
19 citations
,
December 2020 in “Plastic and Reconstructive Surgery” This article reviews the use of platelet-rich plasma for skin rejuvenation and hair regrowth, noting positive outcomes despite variability in preparation and a lack of standardized protocols.
19 citations
,
August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
19 citations
,
June 2019 in “Clinical Drug Investigation” This study concluded that platelet-rich plasma injections significantly improved hair density, thickness, and scalp inflammation in both male and female pattern hair loss, with better outcomes in lower-grade cases.
19 citations
,
May 2019 in “Journal of Cosmetic Dermatology” In this study, both platelet-rich plasma and intralesional corticosteroids improved hair re-growth in alopecia areata patients, but the difference between treatments was not significant, with fewer relapses observed in the platelet-rich plasma group.
19 citations
,
May 2017 in “Dermatologic Surgery” Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.
19 citations
,
January 2017 in “International Journal of Trichology” This study found that a standardized PRP application protocol was effective as a coadjuvant therapy in most patients with androgenetic alopecia who did not respond to minoxidil or finasteride, based on improvements in Ebling's scale.
19 citations
,
September 2013 in “Molecular Medicine Reports” In this study, researchers developed a method to efficiently derive contractile smooth muscle cells from human hair follicle stem cells using TGF-β1 and PDGF-BB, which may advance vascular tissue engineering.
19 citations
,
January 2010 in “Hair transplant forum international” This abstract describes the components found in the alpha and dense granules of platelets, but it provides no new research findings.
18 citations
,
March 2022 in “Drug design, development and therapy” This review examines the definition, classification, mechanism, clinical efficacy for hair regrowth, and potential adverse effects of platelet rich plasma, but does not present new experimental results.
18 citations
,
April 2021 in “PLOS ONE” This systematic review found that most level I/II clinical studies on platelet-rich plasma therapy have focused on musculoskeletal injuries, but inconsistent reporting of PRP composition complicates comparisons across medical specialties.
18 citations
,
July 2020 in “Journal of The American Academy of Dermatology” This study found that PRP injections using the Eclipse system significantly improved hair density and caliber in women with androgenetic alopecia compared to saline placebo at 24 weeks.
18 citations
,
January 2020 in “Indian Dermatology Online Journal” This review summarizes available evidence on the dermatological use of platelet-rich plasma, particularly noting its efficacy for androgenetic alopecia and skin rejuvenation, but highlights significant gaps due to limited high-quality studies.
18 citations
,
January 2019 in “International Journal of Trichology” This study found that PRP therapy resulted in better hair growth and patient satisfaction than minoxidil therapy in men with androgenetic alopecia over six months, and patients with higher platelet counts in PRP experienced greater improvement.
18 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.
18 citations
,
November 2016 in “Journal of Oral and Maxillofacial Surgery” This review discusses platelet-rich plasma for androgenic alopecia and reports beneficial effects on hair density and quality, but suggests more rigorous studies are needed for conclusive evidence.
18 citations
,
July 2007 in “Hair transplant forum international” This study reported that using platelet-rich plasma as a storage medium for hair grafts in hair restoration surgery may improve graft survival rates and accelerate healing.
17 citations
,
March 2023 in “Journal of Clinical Medicine” This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa.
17 citations
,
March 2021 in “Expert Opinion on Biological Therapy” This review analyzes the impact of different preparation methods for platelet-rich plasma, human follicles stem cells, and adipose-derived stem cells on hair regrowth and wound healing, but reports no new results; the authors emphasize convincing evidence of positive outcomes despite protocol variability.
17 citations
,
May 2005 in “Hair transplant forum international” This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.
16 citations
,
July 2022 in “The Laryngoscope” This study found that platelet-rich plasma injections for vocal fold scarring and atrophy showed a favorable safety profile and subjective improvements in vocal quality and fatigue over a three-month follow-up.
16 citations
,
October 2021 in “Techniques in Coloproctology” This study found that using autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma may improve healing rates in patients undergoing flap repair for transsphincteric cryptoglandular fistulas.
16 citations
,
January 2021 in “International Journal of Medical Sciences” This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.
16 citations
,
November 2020 in “Military Medical Research” This review discusses the potential therapeutic role of platelet-rich plasma in treating military drill injuries, such as plantar fasciitis and stress fractures, but reports no new clinical findings.
16 citations
,
March 2020 in “Facial Plastic Surgery Clinics of North America” The authors concluded that platelet-rich plasma (PRP) shows promising potential as a safe treatment for hair restoration in androgenic alopecia, though further research is needed to refine its use and confirm long-term effects.
16 citations
,
December 2019 in “Journal of Cellular and Molecular Medicine” This study found that sonicated platelet-rich plasma was more effective than calcium chloride-induced platelet-rich plasma in activating hair follicle stem cells and promoting hair follicle regeneration in mice.