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    Glossary Platelet Lysate

    substance from broken-down platelets, rich in growth factors

    Platelet Lysate (PL) is a substance derived from the breakdown of platelets, which are small cell fragments in the blood involved in clotting. It is rich in growth factors and cytokines, making it useful in regenerative medicine and tissue repair, including treatments for hair loss and alopecia.

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    1. Platelet lysate: a promising candidate in regenerative medicine Regenerative Medicine · 2021 · 13 citations
    2. Molecular Insights into the Superiority of Platelet Lysate over FBS for hASC Expansion and Wound Healing Cells · 2025 · 2 citations
    3. Platelet lysate promotes hair growth: In vitro and in vivo mechanism and randomized, controlled trial Biomedicine & pharmacotherapy · 2023 · 2 citations
    4. Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: Are we ready for clinical use? Journal of cellular physiology · 2019 · 51 citations
    5. Preparation of super-activated platelet lysate and its effect on hair follicle regeneration in a mouse model of androgenetic alopecia Int J Biologicals · 2020
    6. Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways Biomedicine & Pharmacotherapy · 2016 · 11 citations
    7. Application of platelet-rich plasma lysate combined with hyaluronic acid microneedles for the treatment of alopecia Drug Delivery and Translational Research · 2025
    8. PRF Lysates Modulate Chemokine Expression in Oral Squamous Carcinoma and Healthy Epithelial Cells Bioengineering · 2024 · 2 citations
    9. Alopecia and platelet-derived therapies Stem cell investigation · 2017 · 23 citations
    10. Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring RSC Advances · 2026
    11. Platelet-Rich Plasma and its Derivatives for Tissue Engineering BENTHAM SCIENCE PUBLISHERS eBooks · 2023
    12. PROSPECT OF UTILIZING EXPIRED HOMOLOGOUS PLATELET CONCENTRATES AS AN ALTERNATIVE SOURCE OF GROWTH FACTORS AND CYTOKINES IN CLINICAL SETUP FOR BETTER WOUND CARE AND HEALING Asian Journal of Pharmaceutical and Clinical Research · 2024
    13. In vitro expansion of human mesenchymal stem cells and hepatocytes using purified platelet derived growth factors, a potential therapeutic modality for liver fibrosis Egyptian journal of Immunology · 2023
    14. Special Issue “Recent Progress in Regenerative Therapy Using Blood-Derived Biomaterials” International Journal of Molecular Sciences · 2026
    15. Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine bioRxiv (Cold Spring Harbor Laboratory) · 2026
    16. Targeting Adult Mesenchymal Stem Cells Plasticity for Tissue Regeneration Stem Cells International · 2017 · 3 citations
    17. Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth PloS one · 2014 · 102 citations
    18. Platelet-Rich Plasma in Regenerative Medicine: Biological Mechanisms, Preparation Methods, Clinical Applications, and Current Challenges International Research Journal of Innovations in Engineering and Technology · 2025
    19. Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia Dermatologic Surgery · 2019 · 39 citations
    20. Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation Biomedicines · 2021 · 14 citations
    21. Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway Stem Cell Research & Therapy · 2021 · 39 citations
    22. Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways Journal of Cosmetic Dermatology · 2013 · 39 citations
    23. The mechanism of activated platelet‐rich plasma supernatant promotion of hair growth by cultured dermal papilla cells Journal of Cosmetic Dermatology · 2019 · 14 citations
    24. Autologous Platelet Concentrates in Periodontology : Science, Concept, Protocols and Clinical Applications 2025
    25. 832 Variability in secretion of growth factors by platelets is intrinsic to alopecia patients undergoing platelet-rich plasma therapy Journal of Investigative Dermatology · 2020
    26. Current Concepts and Translational Uses of Platelet Rich Plasma Biotechnology InTech eBooks · 2015 · 12 citations
    27. Application of Platelet-Rich Plasma as a Stem Cell Treatment - anAttempt to Clarify a Common Public Misconception Current Molecular Medicine · 2023 · 3 citations
    28. Platelet Rich Plasma Effects on Diabetic Foot Ulcers - A Review National Journal of Health Sciences · 2023 · 3 citations
    29. Comparative study of the therapeutic efficacy of autologous platelet-rich plasma and honey in healing skin wounds in sheep Veterinary World · 2021 · 3 citations
    30. PLATELET-RICH PLASMA AND PLATELET FIBRIN: STANDARDIZED PREPARATION PROTOCOLS, MECHANISMS OF ACTIVATION, STORAGE STABILITY, AND REGULATORY FRAMEWORKS Eastern Ukrainian Medical Journal · 2025