December 2025 in “International Journal of Innovative Technologies in Social Science” This review outlines that minoxidil (topical and oral) and 5α-reductase inhibitors are the most effective treatments for androgenetic alopecia, with additional therapies like platelet-rich plasma and hair transplantation enhancing results, emphasizing the need for individualized, combination approaches.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
December 2025 in “Molecules” This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.
November 2025 in “IECCMEXICO” This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles.
November 2025 in “Aesthetic Surgery Journal Open Forum” This meta-analysis reported that platelet-rich plasma significantly improved patient satisfaction and objective efficacy in treating skin aging, while not significantly increasing adverse effects.
October 2025 in “Asian Journal of Oral Health and Allied Sciences” In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.
August 2025 in “Regenerative Therapy” In this study, researchers observed that platelet-rich plasma-derived exosomes significantly promoted hair regeneration in a murine model of alopecia by enhancing hair follicle stem cell activities and modulating the SIRT1/FoxO3a pathway, suggesting potential clinical benefits for alopecia treatment.
August 2025 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study suggests that noninvasive carboxytherapy methods, like gel formulations and device-assisted delivery, can significantly improve skin conditions with high safety and no recovery time, particularly in sensitive areas.
This review found that exosome therapy shows the most promise for hair regrowth and safety in treating androgenetic alopecia, surpassing platelet-rich plasma, while minoxidil remains less effective but more accessible. Further research is needed to refine these treatments.
July 2025 in “Journal of Dermatological Treatment” This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.
May 2025 in “The Open Biomedical Engineering Journal” This review discusses the use of adipose tissue and platelet-rich plasma in tissue repair and regeneration, noting their promise in surgical outcomes but emphasizing the need for further research to optimize therapies.
April 2025 in “Diagnostics” This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.
April 2025 in “Regenerative Therapy” This study found that PRP-Exos may stimulate hair follicle growth and enhance regeneration in cases of AGA by activating the Wnt/β-Catenin signaling pathway, showing potential both in vitro and in vivo.
March 2025 in “Nepal Journal of Dermatology Venereology & Leprology” This study observed that Nepalese dermatologists commonly manage telogen effluvium with counseling and supplements, despite the lack of a consensus management guideline.
This review highlights new treatment options for alopecia, including JAK inhibitors and Wnt pathway-targeting therapies, which may offer better efficacy and safety than traditional treatments like minoxidil and finasteride, but notes the need for more research on long-term effects and patient-specific responses.
January 2025 in “Bioengineering” This study evaluated the long-term effects of combining autologous platelet-rich stroma injection with transanal advancement flap repair for cryptoglandular transsphincteric fistulas and found that it resulted in primary clinical closure and radiological healing in a high percentage of patients, with low recurrence rates.
January 2025 in “Annals of Dermatology” This review discusses current and emerging treatments for androgenetic alopecia, covering mechanisms, efficacy, and safety of both androgen-targeted and non-androgen-targeted approaches, but reports no new clinical results.
January 2025 in “Dialnet (Universidad de la Rioja)” In this multicenter study, adipose-derived stem cell-enriched fat grafting achieved higher satisfaction and better clinical outcomes compared to platelet-rich plasma and hyaluronic acid filler in aesthetic interventions.
December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
November 2024 in “Journal of Cosmetic Dermatology” This study found that using platelet-rich plasma alongside minoxidil and finasteride/spironolactone during hair transplant surgery for androgenetic alopecia improved follicle survival, hair growth rates, and hair strength.
October 2024 in “Cosmetics” This study found that while most women reported aesthetic improvement after PRP facial injections, objective skin analyzer data showed no significant changes, but midface volume improvement was more likely in those with lower platelet counts and higher estradiol levels.
August 2024 in “PLoS ONE” This study reviewed randomized controlled trials to assess whether adding platelet-rich plasma injections to a Minoxidil regimen offers any benefit in treating androgenetic alopecia, but results are not reported in the abstract.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
May 2024 in “Journal of Education, Health and Sport” This review article highlights the complexity of treating folliculitis decalvans, emphasizing the role of systemic antibiotics like rifampicin and clindamycin as common treatments, while also discussing promising novel therapies, including biological agents, that require further clinical trials to assess their effectiveness and safety.
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
April 2024 in “Archiv EuroMedica” This study found that platelet-rich plasma therapy increased hair density in androgenetic alopecia and improved hair regrowth in chronic plaque alopecia, with better results when combined with minoxidil rather than finasteride.
February 2024 in “Sohag Medical Journal” This review discusses the challenges in treating alopecia areata and the potential psychological impact, noting that spontaneous hair regrowth often occurs and highlighting the consideration of psychotherapy alongside treatment options; it reports no new experimental results.
January 2024 in “International Journal of Dermatology Research” In this study, platelet-rich plasma therapy was observed to provide better improvement in hair regrowth for alopecia areata patients than intralesional triamcinolone acetonide, as measured by lower SALT scores.
November 2023 in “Periodontology 2000” This narrative review examines the technological advancements and clinical applications of liquid injectable platelet-rich fibrin (i-PRF), discussing its use across regenerative periodontology, sports medicine, and more, as well as its potential as a drug delivery system.