5 citations
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August 2021 in “Clinics in dermatology” This review examines the use of platelet-rich plasma in aesthetic medicine and reports no new clinical results, highlighting the need for further research into its efficacy and safety.
April 2026 in “Stem Cell Research & Therapy” This systematic review reports that regenerative medicine therapies, such as conditioned media, platelet-rich fibrin, and stem cells, show promising efficacy and safety in treating androgenetic alopecia, though heterogeneity in study protocols and limited long-term data emphasize the need for further research to optimize these strategies.
This study found that platelet-derived extracellular vesicles from apheresis platelets may effectively activate dermal papilla cells and promote hair follicle growth in a mouse model of hair regeneration.
This article highlights that research is currently indicating platelet-rich plasma therapy as a promising treatment for certain types of baldness, addressing the psychological impact of alopecia.
1 citations
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December 2023 in “Life” This article discusses the potential role of telocytes in skin regeneration and the need to understand their interaction with platelet-rich plasma, reporting no new experimental results.
1 citations
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February 2021 This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.
27 citations
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February 2023 in “Oxidative Medicine and Cellular Longevity” This study found that platelet-derived mitochondria can promote wound healing by reducing oxidative stress-induced apoptosis in vascular endothelial cells, with survivin identified as a potential target.
39 citations
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January 2021 in “BioMed Research International” This review explores the variability in platelet-rich plasma therapy outcomes across different medical applications, attributing disparities to inconsistent blood processing methods, and it reports no new clinical results.
33 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
30 citations
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April 2020 in “Stem Cell Research & Therapy” This study found that the PI3K-Akt signaling pathway is essential for regenerating new hair follicles when epidermal stem cells and skin-derived precursors are combined, suggesting potential therapeutic applications for hair regeneration.
2 citations
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November 2023 in “Journal of Cosmetic Dermatology” This review examines the bibliometric landscape of research on platelet-rich plasma in cosmetic therapy from 2001 to 2022 and reports no new clinical findings, but highlights research trends and future directions.
1 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
This review reports that hair follicles are dynamic neuro-immuno-endocrine organs with intrinsic signaling pathways, which play a crucial role in hair disorders like alopecia. It highlights emerging regenerative approaches targeting these pathways for hair restoration.
May 2024 in “Open Access Journal of Disease and Global Health” This qualitative study reported that platelet-rich plasma treatments improved patient satisfaction and quality of life by enhancing facial texture and hair quality, supporting PRP as a viable option for conditions like alopecia and skin rejuvenation.
December 2023 in “Medicine” This study observed that platelet-rich gel for scalp defect reconstruction was more cost-effective and less painful but resulted in poorer hair growth compared to the external tissue expansion technique.
May 2023 in “Elsevier eBooks” This study found that platelet-rich plasma may be an effective adjuvant treatment for androgenetic alopecia, especially when combined with antiandrogenetic medications and topical minoxidil, though factors like patient age and family history could influence outcomes.
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma with microneedling is effective for hair loss, but the number of sessions needed varies.
June 2020 in “Journal of Investigative Dermatology” This study reports that extracellular microvesicles isolated from stimulated dermal fibroblasts enhanced hair follicle growth ex vivo and identified norrin as a novel modulator in hair regeneration processes.
September 2018 in “Facial Plastic Surgery Clinics of North America” Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.
July 2018 in “Plastic and Aesthetic Nursing” This research abstract provides information about the publisher, Wolters Kluwer Health, and the journal's subscription services, but it doesn’t describe a specific study or research findings. Results are not reported.
November 2025 in “International Journal of Advanced Research” In this case report, PRP therapy led to almost complete clearance of hypopigmentation in a 28-year-old Caucasian female after laser hair removal, suggesting PRP could be a promising treatment option for various hypopigmentation conditions.
November 2025 in “Journal of Clinical Medicine” This study found that platelet-rich plasma may improve patient-reported outcomes for scar symptoms like pain and itching at six months, although no significant changes in scar appearance were observed at three months.
May 2020 in “Journal of the Dermatology Nurses’ Association” This study concluded that using a multimedia patient education tool may improve patient comprehension of platelet-rich plasma treatment for androgenetic alopecia in a dermatology practice.
March 2026 in “Open MIND” This review evaluates PRP, microneedling, and LLLT for alopecia and telogen effluvium, reporting improvements of 30-40% but offers no new clinical data.
29 citations
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December 2019 in “Transfusion and Apheresis Science” This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.
8 citations
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January 2020 in “Indian Dermatology Online Journal” In this study, PRP injections showed comparable effectiveness to triamcinolone for alopecia areata, with a significant decrease in SALT score at one interval, and 12.5% of patients in the PRP group experienced excellent hair regrowth compared to none in the triamcinolone group.
7 citations
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October 2024 in “Cells” This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.
3 citations
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August 2020 in “PubMed” This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.
2 citations
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April 2024 in “International Wound Journal” Combining UV therapy with PRP heals chronic wounds faster and reduces pain.