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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.

Hair shedding is an active process that could be targeted to treat hair loss.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

S100A3 protein is crucial for hair shaft formation in mice.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Cell aging can be both good and bad for tissue repair.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.