December 2025 in “Lviv clinical bulletin” This review found that platelet-rich plasma therapy may enhance ovarian repair and fertility outcomes in ovarian insufficiency, but notes that optimal usage and long-term effects require further investigation.
August 2025 in “Research Square (Research Square)” This study observed that among male patients who experienced telogen effluvium after platelet-rich plasma treatment for androgenic alopecia, there were elevated levels of TNF-α, androgen receptors, and altered 5α-reductase gene expression, suggesting these factors as potential contributors to this unintended outcome.
March 2025 in “Journal of Endocrinology and Metabolism” This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
July 2024 in “Bozok Tıp Dergisi” This study found that using a new method to apply platelet-rich plasma during surgery improved early outcomes for patients with hip avascular necrosis, including those with a history of Covid-19.
May 2024 in “Journal of drug delivery and therapeutics” This literature review suggests that platelet-rich plasma therapy shows promise for improving hair density and patient satisfaction in men with androgenetic alopecia, though standardized protocols are still needed.
August 2023 in “International journal of medical science and clinical research studies” This review discusses platelet-rich plasma (PRP) therapy for pediatric surgical wound care, evaluating its potential as an adjunctive treatment, but reports no new clinical results.
January 2019 in “Springer eBooks” Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
June 2020 in “Aesthetic Surgery Journal” This study found that PRP with high estrogen levels increased hair density more effectively and earlier than autologous PRP in male patients with androgenic alopecia.
13 citations
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February 2024 in “Cureus” This review discusses the emerging role of platelet-rich plasma in bone healing and reports no new clinical results; it highlights promising outcomes from existing research and calls for further standardization and exploration in this field.
7 citations
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January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
1 citations
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October 2024 in “Cureus” This review suggests that platelet-rich plasma injections may be an effective treatment for greater trochanteric pain syndrome, but emphasizes the need for more high-quality trials to confirm these findings.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
January 2024 in “Wiadomości Lekarskie” This study found that using a combined LH and FSH stimulation protocol significantly increased clinical pregnancy rates in women with low ovarian reserve compared to the standard protocol.
110 citations
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August 2015 in “Neuropsychopharmacology” In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.
25 citations
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January 2006 in “British Journal of Dermatology” This study found that finasteride decreases DHT/T levels more significantly in the vertex scalp hair than in the occipital hair of patients with male pattern baldness.
2 citations
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December 2013 in “Xenobiotica” This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.
January 2026 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study reported high analytical performance of an RMP for DHT quantification, with the ability to differentiate between 5α-DHT and 5β-DHT isomers, making it suitable for routine assay standardization and clinical sample evaluation.
May 2025 in “Clinical Endocrinology” In this study, metformin was found to reduce prolactin levels in men with hyperprolactinemia and normal hair growth but not in those with androgenic alopecia, suggesting that androgen excess may interfere with metformin's effects on prolactin.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.
29 citations
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May 2018 in “Clinical Endocrinology” This review discusses the differential diagnosis of low-renin hypertension and highlights recent genetic discoveries related to familial forms, but it presents no new clinical results.
76 citations
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April 2013 in “PLoS ONE” The researchers reported that reactive oxygen species regulate the stress-induced SP-Mast cell pathway, which might support using antioxidants to treat stress-related hair loss.
29 citations
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September 1983 in “British Journal of Dermatology” This study found that men with androgenetic alopecia had significantly lower levels of sex hormone binding globulin and higher salivary testosterone compared to controls, while plasma testosterone levels did not differ.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
5 citations
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August 1987 in “Andrology” This study found that salivary testosterone levels were significantly lower in oligospermic and azoospermic men compared to normal men, suggesting its potential use in assessing male androgen status.
4 citations
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November 2016 in “Archives of Endocrinology and Metabolism” This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.
3 citations
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January 2012 in “Internal Medicine” In this case study, a 68-year-old woman was diagnosed with central diabetes insipidus and hypothalamic hypopituitarism due to a Rathke's cleft cyst.
August 2023 in “International Journal For Multidisciplinary Research” This case study reported that using the ayurvedic treatment protocol of Nitya Virechana, Kulatthadi Kashaya, and Shatapushpa Churna was associated with improved menstrual regularity, reduced obesity, and decreased symptoms of hirsutism and acne in a 19-year-old woman with PCOD.
February 2022 in “Mediators of Inflammation” This study found that reduced plasma DIAPH1 levels were associated with polycystic ovary syndrome, suggesting DIAPH1 as a potential predictive factor for the condition.