7 citations
,
April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The authors concluded that plasma levels of 3α-diolG, ADTG, and DHTG in women with hyperandrogenic disorders primarily reflect adrenal androgen contributions rather than peripheral action, suggesting a potential index for treatment effectiveness.
20 citations
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November 1968 in “The Lancet” This study found that during dialysis, lower plasma-potassium levels were associated with hyperglycemia, suggesting potassium correction is vital when using glucose-rich dialysate.
73 citations
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July 2013 in “The Journal of Sexual Medicine” This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.
5 citations
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May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
50 citations
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July 2014 in “International Journal of Clinical Pharmacology and Therapeutics” This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.
April 2016 in “Journal of The American Academy of Dermatology” People with hair loss have low zinc levels; zinc supplements and laser therapy may help.
In this study, a copper-deficient diet in rats led to a significant decrease in blood and liver copper levels without causing clinical symptoms, while hair leachable copper and bone copper remained unchanged.
32 citations
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January 1990 in “Clinical Endocrinology” This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.
February 2022 in “Mediators of Inflammation” This study found that reduced plasma DIAPH1 levels were associated with polycystic ovary syndrome, suggesting DIAPH1 as a potential predictive factor for the condition.
2 citations
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January 2022 in “Genetics Research” This study found that using hemocoagulase combined with platelet-rich plasma during total hip replacement surgery led to reduced perioperative blood loss and improved early joint range of motion in osteoarthritis patients.
1 citations
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August 2023 in “Journal of Dentomaxillofacial Science” This study found that freeze-dried homologous platelet-rich plasma (FD HPRP) increased osteocalcin levels in cultured osteoblasts, suggesting its potential to support bone regeneration in periodontal treatment.
April 2022 in “International Journal of Health Sciences (IJHS)” This study found that combining low-level light therapy with platelet-rich plasma significantly improved hair parameters in men with androgenic alopecia, although most improvements decreased after treatment stopped.
This study conducted a comparative analysis of platelet rich plasma and low level laser therapy for androgenetic alopecia but does not present new clinical findings.
2 citations
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February 2023 in “Shiraz E-Medical Journal” In this study, low-level laser therapy significantly improved the mechanical strength of bone at tooth extraction sites in rats, while neither platelet-rich plasma alone nor combined with laser affected mechanical strength or calcium content.
1 citations
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January 2022 in “Open Access Macedonian Journal of Medical Sciences” This study observed that PRP treatment resulted in greater improvement in hair thickness and density in alopecia areata patients compared to LLLT, with benefits sustained over 12 weeks.
January 2026 in “Journal of Aesthetic Nursing” This case report observed marked hair regrowth in a patient with refractory alopecia areata using a combination of platelet-rich plasma, low-level light therapy, and microneedling alongside topical and oral agents.
January 2024 in “Biological trace element research” In this study, isotretinoin treatment for acne vulgaris was associated with changes in plasma phosphorus, potassium, magnesium, and zinc levels, potentially affecting kidney function and contributing to side effects like fatigue and dry skin.
7 citations
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January 2017 in “Indian Journal of Dermatology, Venereology and Leprology”
May 2025 in “Clinical Endocrinology” In this study, metformin was found to reduce prolactin levels in men with hyperprolactinemia and normal hair growth but not in those with androgenic alopecia, suggesting that androgen excess may interfere with metformin's effects on prolactin.
20 citations
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July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
June 2020 in “Aesthetic Surgery Journal” This study found that PRP with high estrogen levels increased hair density more effectively and earlier than autologous PRP in male patients with androgenic alopecia.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
51 citations
,
March 2004 in “Hormone and Metabolic Research” This study found that women with PCOS have higher ghrelin levels compared to controls, with ghrelin negatively correlating with BMI and insulin levels, suggesting its potential role in PCOS etiology.
17 citations
,
October 1980 in “PubMed” In this study, sodium valproate achieved complete seizure control in 82% of children as monotherapy, with higher plasma levels potentially linked to resistant cases.
13 citations
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March 2023 in “International Journal of Molecular Sciences” This study found that lower levels of Gas6 and sAxl were independently associated with a history of hair loss following COVID-19, which spontaneously resolved in most cases.
April 2018 in “Journal of Investigative Dermatology” This study found that plasma cardiac troponin I levels were highest in subjects with alopecia areata, potentially indicating increased heart remodeling and a need for close cardiovascular monitoring in these individuals.
December 2024 in “The New Indian Journal of OBGYN” This study, assessing PCOS patients, found a significant positive correlation between increased ovarian volume and elevated insulin resistance, suggesting that larger ovaries may indicate a higher degree of insulin resistance.
18 citations
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April 2021 in “PLOS ONE” This systematic review found that most level I/II clinical studies on platelet-rich plasma therapy have focused on musculoskeletal injuries, but inconsistent reporting of PRP composition complicates comparisons across medical specialties.
8 citations
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December 2023 in “International Journal of Molecular Sciences” In this study, successful treatment outcomes with platelet-rich plasma injections in patients with IC/BPS and rUTI were associated with specific cytokine concentrations, particularly lower TNF-α levels.
March 2025 in “Salud Ciencia y Tecnología” This study found that patients with androgenetic alopecia were generally satisfied after receiving six sessions of PRP mesotherapy combined with nocturnal minoxidil 5% application.