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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Skin problems are very common in people with end-stage kidney disease.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Flutamide reduces hair growth better but has more side effects.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.