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960-990 / 1000+ resultsresearch Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality
Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.
![Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing](/images/research/1ea05caa-3318-4432-b101-9cb88c4959e3/small/20727.jpg)
research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
![Female pattern alopecia: current perspectives](/images/research/037d7db7-1c3a-467a-ab65-f5376f2d12eb/small/14455.jpg)
research Female pattern alopecia: current perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
![Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons](/images/research/afcf4b9e-6b6f-49e5-93af-418179f67f80/small/13100.jpg)
research Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons
The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
![Skin, hair and beyond: the impact of menopause](/images/research/df92a665-e34b-4e85-9fe4-5c976b139649/small/16969.jpg)
research Skin, hair and beyond: the impact of menopause
Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
![Male pattern baldness and incidence of prostate cancer](/images/research/aa400275-22d6-444c-a4e5-5f9c044c8d89/small/13623.jpg)
research Male pattern baldness and incidence of prostate cancer
Men with vertex baldness may have a higher risk of developing prostate cancer, but more research is needed to confirm this.
research Expert consensus on the management of androgenetic alopecia in India
research How actual is the treatment with antiandrogen alone in patients with polycystic ovary syndrome?
Antiandrogens help manage PCOS symptoms but need careful monitoring.
![The post-finasteride syndrome: possible etiological mechanisms and symptoms](/images/research/c399c314-7dd7-4327-b11a-53c9de7a94ff/small/31716.jpg)
research The post-finasteride syndrome: possible etiological mechanisms and symptoms
Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
![Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome](/images/research/219b6a2d-d8ec-4f7e-ac9c-8a9bb5438a4d/small/16602.jpg)
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
![Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases](/images/research/aa3c29db-e5f0-4f08-b59d-3c653d4ea39e/small/16785.jpg)
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
![The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review](/images/research/c605d21b-b9df-443e-9403-dd5dc35f0b1e/small/16530.jpg)
research The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
![Obesity in Adults: Position Statement of Polish Association for the Study on Obesity, Polish Association of Endocrinology, Polish Association of Cardiodiabetology, Polish Psychiatric Association, Section of Metabolic and Bariatric Surgery of the Association of Polish Surgeons, and the College of Family Physicians in Poland](/images/research/8f9ff664-b007-4f4e-9a29-0736456da1c4/small/16682.jpg)
research Obesity in Adults: Position Statement of Polish Association for the Study on Obesity, Polish Association of Endocrinology, Polish Association of Cardiodiabetology, Polish Psychiatric Association, Section of Metabolic and Bariatric Surgery of the Association of Polish Surgeons, and the College of Family Physicians in Poland
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
![The Multiple Consequences of Obesity](/images/research/45a39abd-83b9-4548-9cef-2a6ad8654821/small/13035.jpg)
research The Multiple Consequences of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
![Annual Convention in the Time of COVID](/images/research/2da15398-1fa6-4c6c-9844-b7a832f00051/small/15786.jpg)
research Annual Convention in the Time of COVID
The convention discussed various skin conditions and treatments, and highlighted the importance of vaccinations for patients on immune-altering medications.
![Polycystic Ovary Syndrome: Explaining the Gynecological Aspects and Treatment Options to Patients](/images/research/d1ef56c3-729a-4731-be73-8a847ef1e3fb/small/14173.jpg)
research Polycystic Ovary Syndrome: Explaining the Gynecological Aspects and Treatment Options to Patients
Understanding Polycystic Ovary Syndrome (PCOS) and its causes can lead to effective treatments.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
![Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia](/images/research/5a46c3f2-f753-4bc2-9789-0cd75627f5cf/small/16470.jpg)
research Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
The study suggests that analyzing DNA can help treat hair loss, but more research is needed.
![174 Changes in urine androgen and PG levels during finasteride treatment](/images/research/2a451c65-6f49-4340-9364-14dd18ff5a2d/small/4601.jpg)
research 174 Changes in urine androgen and PG levels during finasteride treatment
Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.
![PLASMA TESTOSTERONE GLUCOSIDURONATE: A RELIABLE INDICATOR OF FEMALE HYPERANDROGENISM (IDIOPATHIC HIRSUTISM AND ANDROGENIC ALOPECIA)](/images/research/f90e6882-e6e5-44fd-b0e2-73c11bf86022/small/12387.jpg)
research PLASMA TESTOSTERONE GLUCOSIDURONATE: A RELIABLE INDICATOR OF FEMALE HYPERANDROGENISM (IDIOPATHIC HIRSUTISM AND ANDROGENIC ALOPECIA)
Measuring plasma testosterone glucosiduronate is a reliable way to detect high male hormone levels in women.
![Markers of peripheral androgen action in vivo and in vitro](/images/research/7883872b-c478-4625-929f-1f292adaa563/small/21163.jpg)
research Markers of peripheral androgen action in vivo and in vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
![Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)](/images/research/d3a519ad-e1ea-47f8-b3e8-c1d89cb56209/small/12304.jpg)
research Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)
The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
![Effects of Finasteride (MK-906), a 5<i>α</i>-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*](/images/research/e9c6e066-528b-48e3-b1af-cfd12bf1de95/small/1933.jpg)
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*
Finasteride safely lowers DHT levels without affecting testosterone.
![Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach](/images/research/8c2dd6b3-3b51-49be-b1e3-f4198a06a0b8/small/13150.jpg)
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
![A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation](/images/research/f52ab12a-ca9a-4c96-b105-312119fb5672/small/31753.jpg)
research A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
![Significance of the polyglutamine tract polymorphism in the androgen receptor](/images/research/97cd8c5b-3ec8-4347-83e3-97c8ddfb1f64/small/15459.jpg)
research Significance of the polyglutamine tract polymorphism in the androgen receptor
The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
![Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases](/images/research/b462824e-f94c-459b-809e-72dbf27e203e/small/13950.jpg)
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
![Effects of Curcumin on Glycemic Control and Lipid Profile in Polycystic Ovary Syndrome: Systematic Review with Meta-Analysis and Trial Sequential Analysis](/images/research/b2337de4-571f-4926-95c5-13f1784126cf/small/23853.jpg)
research Effects of Curcumin on Glycemic Control and Lipid Profile in Polycystic Ovary Syndrome: Systematic Review with Meta-Analysis and Trial Sequential Analysis
Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.
![Androgenetic alopecia: An autosomal dominant disorder](/images/research/e8dbe281-d12a-4b68-ab8a-fb7c57095328/small/2059.jpg)
research Androgenetic alopecia: An autosomal dominant disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.