3 citations
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January 2014 in “Arhiv za farmaciju” This article discusses the role and potential of plant stem cell extracts in cosmetics for their antioxidant and protective effects on skin cells, reporting no new clinical results; the authors highlight ecological and sustainable production methods.
In this research presented at the BEYOND Biohacking Conference 2026, a regenerative skincare serum using plant-derived Consortia Factors® showed significant age spot lightening and improvements in skin smoothness, firmness, and radiance over eight weeks in a study with 35 women.
4 citations
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June 2022 in “Frontiers in Cell and Developmental Biology” Plant extracts might help control stem cell growth for medical use.
February 2026 in “Molecular and Cellular Probes” This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.
May 2026 in “Medical Sciences” This review found that vesicle-based therapies, including mammalian MSC-derived and plant-derived vesicles, consistently promote wound healing in preclinical models of thermal injury and may offer a safer alternative to live cell transplants.
67 citations
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June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
August 2024 in “Applied Sciences” This review explored the causes of hair graying and evaluated how plant-derived extracts and phytochemicals might alleviate it, noting that certain compounds showed potential in enhancing melanocyte function, reducing oxidative stress, and influencing stress-related pathways based on experimental evidence.
July 2026 in “Plastic & Reconstructive Surgery Global Open” This study found that intradermal injections of plant-derived exosomes in adults with early-stage alopecia increased stem cell activity, activated Wnt signaling pathways, and reduced certain immune cell populations, providing insights into their role in hair follicle regeneration and suggesting potential for hair restoration therapy.
9 citations
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November 2018 in “Journal of cosmetic dermatology” This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.
7 citations
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July 2014 in “BMJ case reports” This article reviews the rare skin disorder ichthyosis with confetti, highlighting the potential for future therapies using revertant stem cells, and reports no new clinical results.
June 2025 in “International Journal of Nutrology” In this systematic review, various nutrients and diets, such as a plant-based diet and supplements like omega-3 fatty acids, were found to impact tissue regeneration, skin health, and wound healing, highlighting the role of nutrient-sensitive signaling pathways in these processes.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.
January 2024 in “Cosmetics” In this in-vitro study on human hair follicle cultures, researchers reported that the HAIR & SCALP COMPLEX significantly enhanced hair bulb growth and dermal papilla regeneration compared to other treatments, suggesting a potential new approach for managing hair loss and promoting growth.
106 citations
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August 2021 in “Pharmaceuticals” This review discusses the role of extracellular vesicles in wound healing and explores their potential applications in skin repair and treatment of dermal diseases, reporting no new clinical findings.
3 citations
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September 2025 in “Cosmetics” This review examines the potential and challenges of extracellular vesicles in cosmetics, noting their transformative impact despite regulatory and production hurdles; it reports no new experimental results.
December 2025 in “Pharmaceutics” This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.
October 2025 in “Indian Journal of Dermatology” This study explored recent advancements in hair restoration, particularly focusing on plant-derived exosomes and biomimetic polypeptides, which enhance hair follicle regeneration and growth, offering a promising alternative to human or animal-derived exosomes subject to FDA restrictions.
January 2025 in “Universitätsbibliothek Stuttgart” This article reviews the current challenges, innovations, and prospects of cosmetics designed to prevent hair loss and encourage hair growth, highlighting evolving technologies like gene therapy and the need for multidisciplinary approaches.
April 2026 in “International Journal of Research in Pharmacology & Pharmacotherapeutics” This review highlights the potential of plant-derived bioactive compounds as an alternative to current hair loss treatments by detailing the mechanisms and clinical evidence of eighteen traditional medicinal plants, and discusses future trends like nanotechnology and stem cell therapy in managing alopecia.
December 2025 in “Clinical Case Reports” The exosome injections were from stem cells and plants, not umbilical cords.
This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.
3 citations
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November 2020 in “Planta medica international open” This study reported that plant-produced basic fibroblast growth factor effectively promoted cell proliferation and collagen production in vitro, suggesting potential applications in cosmetics for antiaging and hair growth.
In this study, researchers describe a technique for preparing mesenchymal stem cells to optimize hair transplantation for androgenetic alopecia, highlighting future plans to assess stem cell characteristics and hair density improvements through flow cytometry and trichoscopy.
June 2022 in “Genetic engineering & biotechnology news” This article presents Stemson Therapeutics' development of a stem cell-based approach to generate new hair follicles for treating hair loss, which remains in preclinical stages without tested human results.
January 2016 in “Elsevier eBooks” This review discusses three aspects of cell fate specification across Metazoa and reports no new experimental results, highlighting the formation of nematode equivalence groups, evolution of echinoderm skeletogenic mesoderm, and adult cell fate regulation.
1 citations
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January 2021 in “Journal of Cancer Therapy” This article reviews regenerative medicine strategies, such as stem cells and plant polyphenols, for mitigating radiotherapy side effects but does not present new clinical findings, calling for further investigation.
May 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article reports on the latest therapeutic strategies for alopecia, highlighting advancements in personalized treatment plans, combination therapies, and regenerative approaches, with a focus on improving hair regrowth and minimizing side effects through modern treatments like stem cell therapy and Janus kinase inhibitors.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article examines recent advances in understanding and managing various types of alopecia, highlighting modern therapeutic strategies such as individualized treatment plans, combination therapies, and regenerative approaches aimed at improving hair regrowth and minimizing adverse effects.