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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Current treatments for alopecia show no significant long-term benefits.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Humans lost body hair relatively recently in evolution.

Too much androgen can cause hair loss; finasteride may help.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.