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The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Spironolactone treatment increases the amount of testosterone available in the body.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Stem cell niches support, regulate, and coordinate stem cell functions.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Probiotic bacteria improved skin and hair health in aged mice.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.