research This Month in JAAD: October 2021
Oral baricitinib is effective and safe for treating alopecia areata.
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research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
Saw palmetto extract is effective and safe for treating lower urinary tract symptoms, working as well as certain medications, and works even better in severe cases.
research Clinical Trial of Topical Application of Mixed Complex Fermented Extracts Encapsulated in Poly-Gamma Glutamic Acid Hydrogel Nanoparticles in Patients with Androgenetic Alopecia
The solution increased hair density safely and effectively for hair loss.
research Controversy on the Role of Iron and a Clinical Trial with Intermittent Iron and Nutritional Supplements in Hair Loss Management
Intermittent iron and nutritional supplements can help reduce hair loss.
research Retraction of: Transurethral Resection of Prostate and Bleeding: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial to See the Efficacy of Short-Term Use of Finasteride and Dutasteride on Operative Blood Loss and Prostatic Microvessel Density
The journal retracted an article due to inaccurate statistics and asked the authors to revise and resubmit it.
research Vitamin D Protection Against Acute UV Damage: A Critical Role of Autophagy in the Skin
Vitamin D can reduce skin inflammation caused by UV rays by enhancing cell "fitness" and skin repair.
research Comparative and Randomized Study of Platelet-Rich Plasma in Male Androgenetic Alopecia
Platelet-rich plasma treatment improved hair growth in men with male pattern baldness.
research Hair Loss
Some alternative treatments may help with hair loss, but more evidence is needed to confirm their effectiveness.
research Preparation and Evaluation of a Multimodal Minoxidil Microemulsion Versus Minoxidil Alone in the Treatment of Androgenic Alopecia of Mixed Etiology: A Pilot Study
The multimodal microemulsion with minoxidil, diclofenac, and tea tree oil is more effective for hair growth than minoxidil alone.
research Randomized Therapeutic Trial for Patients with Alopecia Areata
Topical minoxidil, intralesional steroids, and cryotherapy significantly improve alopecia areata.
research Finasteride Reduces Serum PSA to a Similar Extent at 1 mg and 5 mg Daily Doses
Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
research Drug Information Analysis Service: Effectiveness of Cromolyn Sodium in Treating Asthma in Children Under 2 Years Old
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Clinical Evaluation of Hair Regrowth Tonics Containing Oleanolic Acid
The hair regrowth tonic effectively increased hair count and was safe for treating male pattern baldness.
research Men With an Improvement in Urinary Symptoms Have a Lower Risk of Mortality
Men with better urinary symptoms have a lower risk of death.
research Corrigendum
The 7.1% withdrawal rate was in the oral finasteride group, not the topical one.
research Evaluation of the Role of Topical Cetirizine 1% in the Treatment of Male Androgenetic Alopecia
Topical cetirizine helps treat male hair loss.
research Histological Findings of Follicular Units in Patients with Androgenetic Alopecia Before and After Application of Autologous Platelet-Rich Plasma
The effectiveness of APRP for hair loss is unclear due to limited data.
research The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia
Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
research The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia
Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
research Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone
Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
research Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone
Testosterone therapy increases bone density in older men with low testosterone levels.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Corticosteroids for the Treatment of Duchenne Muscular Dystrophy
Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research HIV Pre-Exposure Prophylaxis in Transgender Women: A Subgroup Analysis of the iPrEx Trial
PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
research Treatment of Female Pattern Hair Loss With Oral Antiandrogens
Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
research Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
research Interventions for Alopecia Areata
Current treatments for alopecia show no significant long-term benefits.
research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata
A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.