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Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Certain flavonoids help grow back colored hair after skin injury.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

Targeting ornithine decarboxylase can help prevent skin cancer.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Intermediate filaments are crucial for cell differentiation and stem cell function.

IL-1β inhibits human hair follicle growth.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Deleting TNFα gene reduces skin cancer risk in certain mice.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.

Applying a specific inhibitor lightens skin and hair color.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.