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New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.

Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Improving how drugs are absorbed through the skin could better treat mange in wombats.

The method quickly and accurately measures minoxidil in drugs, comparable to standard techniques.

The study found a way to improve a skin-applied minoxidil formula using a specific design method.

Topical vitamin D is effective in treating vitiligo with few side effects.

Using iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles increases drug release but reduces its targeting to hair follicles.

PCOS is a complex condition linked to hormonal imbalance and insulin resistance, with weight loss being important for management.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.

The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.

Forensic hair analysis for drugs is now more reliable and accurate.

The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Topical finasteride at 0.25% is effective and has fewer side effects than oral finasteride for hair loss.

The microemulsion delivered the dye deeper into the skin than the cream.

Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

ACBP is crucial for healthy skin in mice.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.