research Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans
Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.
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research Impact of Taxol on Dermal Papilla Cells: A Proteomics and Bioinformatics Analysis
Taxol damages hair growth cells, causing hair loss.
research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Polycystic Ovary Syndrome: A Literature Review With a Focus on Diagnosis, Pathophysiology, and Management
PCOS requires personalized treatment to improve life quality and reduce health risks.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice
Prolactin affects when mice shed and grow hair.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Current Concepts of Polycystic Ovary Syndrome
PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
research Desmopressin Stimulation Test as a Valuable Tool in Establishing Cushing Syndrome Etiology
The desmopressin stimulation test helped identify an adrenal cause for a patient's Cushing's syndrome.
research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Neuroimmunoendocrine Circuitry of the Brain-Skin Connection
Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
research Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?
Stress might contribute to hair loss in alopecia areata.
research Regeneration of a Bioengineered 3D Integumentary Organ System from iPS Cells
Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.
research Endocrine Functions of the Testes
The testes produce important hormones like testosterone and others that play key roles in male body functions.
research Generalized Glucocorticoid Resistance
Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
research New Frontiers in Human Hair Follicle Neuroendocrinology
Human scalp hair follicles can produce and respond to several hormones, affecting hair growth and pigmentation.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions
Stress hormones and autoimmune reactions can cause hair loss.
research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Neuroendocrine Determinants of Polycystic Ovary Syndrome
Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.
research Consequences of Anabolic-Androgenic Steroid Abuse in Males: Sexual and Reproductive Perspective
Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
research Corticotropin Releasing Factor-1 Receptor Antagonism Associated With Favorable Outcomes of Male Reproductive Health Biochemical Parameters
Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
research Androgens
Male hormones and their interactions are crucial for male sexual development and characteristics.
research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients
High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
research Effects of Natural Products on Skin Inflammation Caused by Abnormal Hormones Secreted by the Adrenal Gland
Natural products may help treat skin inflammation from abnormal adrenal hormones.
research Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman
Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
research The Effect of EGR1 on the Proliferation of Dermal Papilla Cells
Increasing EGR1 levels makes hair root cells grow faster.