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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

Different PCOS types respond uniquely to infertility treatments, with some having lower pregnancy rates and higher risks of complications.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

TSH is usually the only test needed to check thyroid function in primary care.

Low testosterone levels may lead to more severe COVID-19 outcomes.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The dog recovered from hypothyroidism and regrew its hair after two months of treatment.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.

A woman's symptoms of increased body hair and testosterone were caused by a rare adrenal tumor, which was removed successfully.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

LhGH promotes hair growth and prevents hair loss in mice.

People with certain skin diseases have higher levels of the hormone prolactin in their blood.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.

Some common medications can harm male fertility, but many effects can be reversed.