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PCOS is caused by both genetics and environmental factors like diet and obesity.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

TRH stimulates human hair growth and extends the hair growth phase.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Spironolactone can reduce hair growth in women with hirsutism.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Prolactin slows down hair growth in mice.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.