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Apoptosis is crucial for healthy skin and treating skin diseases.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

Multimodal minoxidil microemulsion is more effective in treating hair loss than minoxidil alone.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Injury changes how hair follicle stem cells behave, depending on the hair growth stage.

Hormones and genes affect hair growth and male baldness.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Angora goat hair grows faster and produces more protein than cashmere goat hair, and certain hormones and nutrients positively affect hair growth and protein synthesis.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

A 3-month treatment improved PCOS symptoms and reduced certain immune proteins.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.