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Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

FFA's causes may include environmental triggers and genetic factors.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Skin cells can help create early hair-like structures in lab cultures.