research Special Focus Issue: Transdermal, Topical, and Follicular Drug Delivery Systems
New drug delivery systems improve treatment effectiveness and patient experience.
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240-270 / 1000+ results research Estrogen Regulates the Expression of Retinoic Acid Synthesis Enzymes and Binding Proteins in Mouse Skin
Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.
research Acne: Diet and Acnegenesis
Eating dairy and high glycemic foods may increase the risk of acne.
research Patterns of Skin Diseases in Qassim Province, Saudi Arabia
Acne is the most common skin issue in Qassim Province, especially among young adults.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle
Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
research Disorders of Excessive Hair Growth in Adolescents
Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.
research Strategic Targets in Acne: The Comedone Switch in Question
The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research Hair Loss in Adult Females: A Clinical and Trichoscopic Study
Most adult women experiencing hair loss are aged 21-40, with the most common type being female pattern hair loss. Trichoscopy is a useful tool for diagnosing different types of hair loss.
research An Updated Review of the Sebaceous Gland and Its Role in Health and Diseases Part 1: Embryology, Evolution, Structure, and Function of Sebaceous Glands
Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
research Role of Stem Cells in Skin Maintenance, Regeneration, and Repair: Focus on Epidermis and Pilosebaceous Units
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells
Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
research A Case of Acne Vulgaris in a 23-Year-Old Female Patient
A 23-year-old woman has Acne Vulgaris, which causes different types of skin bumps and possible scarring.
research The Evolution of Healthy Skin to Acne Lesions: A Longitudinal, In Vivo Evaluation with Reflectance Confocal Microscopy and Optical Coherence Tomography
Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.
research Scalp Basal Cell Carcinoma: A Different Entity?
Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.
research In Vitro Mesenchymal–Epithelial Interaction Facilitates De Novo Hair Follicle Formation
Adult skin cells can be used to create new hair in a lab.
research Alterations in Epidermal Stem Cells Within the Pilosebaceous Unit in Atrophic Acne Scars
Inflammatory acne damages skin stem cells and reduces their growth, leading to atrophic acne scars.
research The Regulatory Biology of the Human Pilosebaceous Unit
Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.
research Hidradenitis Suppurativa: A Folliculotropic Disease of Innate Immune Barrier Dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research Eruptive Vellus Hair Cysts: An Underdiagnosed Entity
Eruptive vellus hair cysts are often missed in diagnoses.
research Activity of Type 1 5α-Reductase Is Greater in the Follicular Infrainfundibulum Compared with the Epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit
Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
research Molecular Interactions of Natural and Synthetic Steroids in Female Hamsters’ Flank Organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Trichoscopy in the Healthy Female: Method Standardization and Norms for Measurable Parameters
Researchers established normal hair and scalp characteristics for healthy women using trichoscopy.
research Cutaneous Toxicities From Transplantation-Related Medications
Skin problems from transplant drugs are common and need careful management in organ transplant patients.
research Comedone Formation: Etiology, Clinical Presentation, and Treatment
Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.
research The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit
Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).