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    Glossary Piloerection

    involuntary hair follicle contraction causing goosebumps

    Piloerection, commonly known as goosebumps, is the involuntary reaction where tiny muscles at the base of hair follicles contract, causing the hair to stand up. This response is typically triggered by cold temperatures or emotional stimuli such as fear or excitement, and is a vestigial reflex inherited from our ancestors, who had more body hair and used this mechanism to appear larger or to trap an insulating layer of air.

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    Research 30 of 94

    1. Single follicular unit transplantation reconstructs arrector pili muscle and nerve connections and restores functional hair follicle piloerection The Journal of Dermatology · 2012 · 13 citations
    2. α<sub>1</sub>-AR agonist induced piloerection protects against the development of traction alopecia Dermatologic Therapy · 2015 · 5 citations
    3. 556 α 1 -AR agonist induced piloerection protects against the development of traction alopecia Journal of Investigative Dermatology · 2016
    4. Beyond goosebumps: Does the arrector pili muscle have a role in hair loss? International Journal of Trichology · 2014 · 31 citations
    5. C‐tactile afferents: The mystery of human emotional touch has been hidden hair‐deep The Journal of Physiology · 2025
    6. Describing the Hair and Related Abnormalities Journal of the Dermatology Nurses’ Association · 2012
    7. 食物アレルギーの診断の進め方 (特集 食物アレルギー;看護ケアに必要な知識とポイント) -- (知っておきたい知識) 小児看護 · 2006
    8. The Acute Toxicity of 2,3,4,7,8-Pentachlorodibenzofuran (4PeCDF) in the Male Fischer Rat Toxicological Sciences · 1988
    9. Faculty Opinions recommendation of Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    10. Hair organ regeneration via the bioengineered hair follicular unit transplantation Scientific Reports · 2012 · 66 citations
    11. Hair follicle germs containing vascular endothelial cells for hair regenerative medicine Scientific Reports · 2021 · 23 citations
    12. Hair Disorders Springer eBooks · 2018
    13. 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis Journal of Investigative Dermatology · 2018
    14. Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches Nature Communications · 2012 · 179 citations
    15. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020 · 77 citations
    16. Styling without shedding: Novel topical formula reduces hair shedding by contracting the arrector pili muscle Dermatologic Therapy · 2017
    17. 559 Visualization of sweat suppression following botulinum toxin A by soluble microneedle arrays Journal of Investigative Dermatology · 2016
    18. 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor Journal of Investigative Dermatology · 2016
    19. Stem cell dynamics, migration and plasticity during wound healing Nature Cell Biology · 2018 · 211 citations
    20. Advances in aesthetic hair restoration Aesthetic Surgery Journal · 2003 · 6 citations
    21. Functional salivary gland regeneration by transplantation of a bioengineered organ germ Nature Communications · 2013 · 165 citations
    22. Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment Stem Cells Translational Medicine · 2013 · 84 citations
    23. Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors Journal of the European Academy of Dermatology and Venereology · 2021 · 37 citations
    24. Experimental and Clinical Pharmacology of<i>Ziziphus jujuba</i>Mills Phytotherapy Research · 2017 · 31 citations
    25. An updated review of the sebaceous gland and its role in health and diseases Part 1: Embryology, evolution, structure, and function of sebaceous glands Dermatologic Therapy · 2020 · 13 citations
    26. Saliva secretion in engrafted mouse bioengineered salivary glands using taste stimulation Journal of prosthodontic research · 2014 · 10 citations
    27. Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration Drug Discovery Today · 2018 · 9 citations
    28. Hair transplantation in mice: Challenges and solutions Wound Repair and Regeneration · 2016 · 3 citations
    29. Post-natal development of rats` offspring treated with the ethanol extract of Neem leaves (<i>Azadirachta indica</i> A. Juss) during pregnancy and lactation Acta Scientiarum Biological Sciences · 2015 · 3 citations
    30. Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 2 citations