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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Androgens can both increase and decrease hair growth in different parts of the body.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Fungi-produced compounds can change plant root growth.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Myrtle has various health benefits and potential for medicine development.

Researchers developed a new model for more realistic computer graphics rendering of hair by considering how light scatters on hair fibers.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Humans lost body hair relatively recently in evolution.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.