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There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.