research Epitestosterone—An Endogenous Antiandrogen?
Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
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research Regulation of Androgen Receptor and 5α-Reductase in the Skin of Normal and Hirsute Women
The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
research The Identity of Flavin with the Cataract-Preventive Factor
Flavin prevents cataracts in young rats.
research Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Ion Pairs of Risedronate for Transdermal Delivery and Enhanced Permeation Rate on Hairless Mouse Skin
Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
research Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
research Effect of Thioredoxin Reductase 1 on Glucocorticoid Receptor Activity in Human Outer Root Sheath Cells
Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
research Comparative Dermatology: Canine Endocrine Dermatoses
Endocrine diseases in dogs often cause skin problems, with hypothyroidism and hyperadrenocorticism being common and leading to hair loss and infections.
research Stress and Psychoneuroimmunologic Factors in Dermatology
Stress and emotional factors can worsen skin conditions by affecting the immune system.
research Minoxidil Increases 17β-Hydroxysteroid Dehydrogenase and 5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Balding Scalp
Minoxidil boosts enzymes that help hair growth.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Effect of Minoxidil on Blood Pressure and Hemodynamics in Severe Hypertension
research Ornithine Decarboxylase Activity in Relation to DNA Synthesis in Mouse Interfollicular Epidermis and Hair Follicles
research Graded Levels of Pyridoxine in the Rat Diet During Gestation and the Physical and Neuromotor Development of Offspring
Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.
research Keratin Formation in the Hair Follicle
Keratin fibrils in hair form and stop growing at specific points in the follicle.
research Some Observations on the Proteins of the Inner Root Sheath Cells of Hair Follicles
research Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia
Microneedles with enhancer effectively promote hair growth and increase hair density.
research Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery
Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
research The Clinical Presentation of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
research Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Transformation of Amnion Epithelium into Skin and Hair Follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research Canine Zinc-Responsive Dermatosis
Dogs with zinc-responsive dermatosis need zinc supplements or dietary changes for treatment.
research Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells
research The Therapeutic Use of Topical Minoxidil
Minoxidil effectively treats hair loss, with better results in women.
research Reversible Ageusia Associated With Losartan
Losartan can cause temporary loss of taste.
research Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research Current Advances in Stem Cell-Based Therapies for Hair Regeneration
Stem cell therapies show promise for hair regrowth but face production and application challenges.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.