TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
[object Object] September 2016 in “Springer eBooks” Gray hair is caused by oxidative stress damaging hair cells.
88 citations,
June 2019 in “Cell reports” Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
14 citations,
November 2013 in “PloS one” HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
2 citations,
November 2022 in “Journal of Biochemistry and Molecular Biology” Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
1 citations,
August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.
December 2022 in “Frontiers in Pharmacology” Tianma Gouteng decoction may help prevent hair loss and promote hair growth.
4 citations,
May 2023 in “Pigment Cell & Melanoma Research” BMI1 is essential for preventing hair greying and maintaining hair color.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
56 citations,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
12 citations,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
August 2023 in “Stem Cell Research & Therapy” A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
26 citations,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
53 citations,
October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
2 citations,
July 2021 in “Genes” A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
[object Object] 222 citations,
August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
36 citations,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
21 citations,
January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
6 citations,
September 2022 in “Frontiers in pharmacology” Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
2 citations,
February 2009 in “Journal of the American Academy of Dermatology” Many research paper titles in dermatology journals lack scientific precision.
8 citations,
April 2016 in “Experimental dermatology” B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
3 citations,
May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
10 citations,
June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
8 citations,
January 1998 in “Journal of Investigative Dermatology” Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
124 citations,
August 1994 in “Journal of Investigative Dermatology” Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.