11 citations
,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” This study reports that treatment with X-rays or procarbazine induced dose-dependent mutations in melanocytes in mouse hair follicles, showing similar mutation rates to previous methods.
19 citations
,
August 1996 in “British Journal of Dermatology” This study found that dermal papillae in alopecia areata, including clinically normal follicles, exhibited ultrastructural abnormalities that suggest an early pathological role in the disease's development.
22 citations
,
October 2021 in “Cold Spring Harbor Perspectives in Biology” This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.
8 citations
,
November 2022 in “International Journal of Cosmetic Science” This review discusses the limitations of current hair classification systems and highlights the need for standardized reporting of key hair characteristics to improve study comparisons; it reports no new results.
10 citations
,
May 1986 in “Experientia” This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.
43 citations
,
October 2005 in “Molecular and cellular endocrinology” This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.
March 2026 in “Dyes and Pigments” This study found that genipin-based pigments, accelerated by riboflavin and blue-light photocatalysis, achieved commercial-level hair dye results with enhanced gloss and excellent color retention while reducing cuticle disruption, offering a potentially safer and faster alternative to traditional hair coloration methods.
30 citations
,
January 2014 in “Annals of Dermatology” This study observed no significant relationship between trichoscopic findings and disease severity in male or female androgenetic alopecia, despite some specific patterns correlating with different severity levels in female patients.
18 citations
,
April 1989 in “Archives of Dermatology” This study found that segmented heterochromic scalp hair associated with iron-deficiency anemia in a teenage girl completely recovered following iron supplementation, suggesting a role for iron in hair pigment production.
This study found that 1064 nm QS Nd:YAG laser treatment effectively lightens hair and improves skin appearance in Indian subjects with minimal adverse effects, offering a safer alternative to chemical lightening products.
January 2026 in “SSRN Electronic Journal” Riboflavin with blue light speeds up hair dyeing, making it faster, safer, and long-lasting with less hair damage.
November 2025 in “Journal of Pharmacy and Pharmacology” This review highlights pigment epithelium-derived factor's roles in ageing and development, focusing on its antioxidant functions and support of stem cell survival, but reports no new experimental results.
11 citations
,
April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
August 2026 in “International Journal of Bioprinting” This review highlights the complexities of hair graying and the limitations of current models to fully replicate hair follicle pigmentary unit function, suggesting that technologies like organoids and bioprinting show promise but require further development for effective hair repigmentation interventions.
35 citations
,
October 2003 in “Dermatologic clinics” This article discusses the lack of national credentialing for laser therapy practitioners and emphasizes the need for rigorous self-assessment and expertise, particularly when treating patients with darker skin, without presenting new research results.
2 citations
,
October 1951 in “Journal of gerontology” This study reported on the excretion levels of pantothenic acid in patients experiencing achromotrichia and alopecia but did not present new clinical results.
21 citations
,
February 2006 in “Clinical Cancer Research” This commentary discusses how microphthalmic-associated transcription factor levels in circulating tumor cells correlate with melanoma progression and suggests the factor may be up-regulated in vivo, but it reports no new clinical results.
8 citations
,
January 2018 in “European journal of dermatology/EJD. European journal of dermatology” The girl's regrown brown hair had less of certain pigments than her original black hair.
3 citations
,
January 2013 in “Journal of cosmetics, dermatological sciences and applications” This study found that the new HCC additive enhances the permeation of pigments and active ingredients into hair, suggesting potential use in developing functional cosmetic hair products.
October 2022 in “Southeast Asian journal of health professionals” This article discusses factors influencing hair greying, such as thyroid hormone levels and postmenopausal changes, and suggests lifestyle adjustments for hair health; it reports no new clinical findings.
8 citations
,
February 2013 in “Central European Journal of Biology” This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.
1 citations
,
September 1984 in “Journal of Biological Education” Plants change their growth in response to shade based on light signals detected by phytochrome.
3 citations
,
July 1969 in “PubMed” This study found that unilateral neutron irradiation in pigs significantly decreased the uptake of radioactive zinc in blood, impaired growth, and led to decreased organ weights and hair pigmentation changes on the irradiated side.
January 2026 in “Current Issues in Molecular Biology” This study found that transfecting alpaca melanocytes with miR-5110 altered gene expression related to pigmentation, specifically identifying pathways like MAPK and Wnt as involved in melanogenesis regulation, providing insights into miR-5110's role in pigmentation processes.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
157 citations
,
December 2015 in “Journal of the American Academy of Dermatology” This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.
17 citations
,
October 2010 in “Pigment cell & melanoma research” This article reviews the impact of H2O2-redox homeostasis on hair follicle pigmentation via tyrosinase and associated mechanisms, discussing primarily findings from murine models without providing new clinical results for humans.
49 citations
,
August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
7 citations
,
June 2021 in “Cell Proliferation” This study found that direct interactions between human dermal papilla cells and melanocytes under low oxygen conditions improved cell functions and could be important for hair regeneration efforts.
1 citations
,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” This study found that lower zinc serum levels may contribute to premature hair graying in college students at Universitas Sumatera Utara.