research Induction of Psoriasiform Changes in Guinea Pig Skin by Propranolol
Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
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research Effect of Deep Dermal Tissue Dislocation Injury on Skin Fibrosis in Pigs
Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
Valproic acid microemulsions improve skin delivery compared to regular solutions.
research Regeneration of Rete Ridges in Lanyu Pig (Sus Scrofa): Insights for Human Skin Wound Healing
Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.
research Topically Active Vitamin D3 Analogue, 1α,24-Dihydroxy-Cholecalciferol, Has an Anti-Proliferative Effect on the Epidermis of Guinea Pig Skin
A vitamin D3 compound can reduce skin cell growth.
research Superoxide Dismutase Loaded Niosomes Delivery to Hair Follicles: Permeation Through Synthetic Membrane and Guinea Pig Skin
Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Determination of Permeation Pathway of Gentamicin into Pig's Ear Skin
Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
Porcine skin is very similar to human skin, making it a useful model for research.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Transdermal Permeation of Drugs in Various Animal Species
Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
research Somatotropin Penetration Testing From Topical Formulations Applied to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals
The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
research Skin Epidermis and Adnexa Regrowth Induced by Treatment With Artificial Dermal Template After Full-Thickness Skin Wound
Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.
research P62 Pre-Clinical Pharmacological and Skin Penetration Profile of LDE255, a Novel and Specific Smoothened Antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research A Novel Microparticle-Based Formulation for Topical Delivery of FOL-005, a Small Peptide
The new skin cream with FOL-005 safely promotes hair growth and is stable and user-friendly.
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research Modulation of Hair Growth by Topical Drug Delivery Enhanced by STAR Particles
STAR particles can improve the effectiveness of topical hair growth treatments without causing skin irritation.
research Polymer Conjugated Retinoids for Controlled Transdermal Delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with less inflammation.
research The Role of Labrasol in the Enhancement of the Cutaneous Bioavailability of Minoxidil in Phospholipid Vesicles
Labrasol® in phospholipid vesicles improves minoxidil delivery to the skin, potentially aiding hair growth treatments.
research Analysis of the Pretreatment Effect of Ethanol on the Stratum Corneum and Hair Follicular Penetration of Drugs Using the Hair Follicle Plugging Method
Ethanol pretreatment affects drug penetration through skin and hair follicles.
research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs
Hair follicles significantly affect the skin absorption of some drugs.
research New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment
New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
research The Failure Behavior of the Anchorage of Hairs During Slow Extraction
Growing hairs are easier to pull out than resting hairs due to different anchorage strengths.
research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Pigmentation of Hair on Transplanted Skin in Hooded Rats
Transplanted skin on hooded rats often grows white hair instead of black.
research Imaging of Zinc Oxide Nanoparticle Penetration in Human Skin In Vitro and In Vivo
Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro
Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.