April 2023 in “Journal of Investigative Dermatology” This study found that inhibiting PI3 kinase in epidermal stem cells reduces YBX1 phosphorylation, thereby decreasing cellular senescence and enhancing wound healing and regeneration in adult-derived skin models.
January 2018 in “Contributions to management science” This review discusses the role of microRNA in skin development and disease, highlighting its potential for novel therapies, and reports no clinical results.
3 citations
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January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
September 2023 in “Дерматовенерология, косметология” In this study conducted at the Vitebsk Regional Clinical Center, digital video microscopy without biopsy effectively identified diagnostic criteria for non-scarring alopecia in 315 patients, allowing for the prescription of appropriate treatments for alopecia areata and androgenetic alopecia.
November 2020 in “Дерматовенерология, косметология” This study found that among men with androgenetic alopecia, the M-type pattern, either isolated or combined with others, was observed most frequently, using the BASP classification.
80 citations
,
April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
27 citations
,
August 2018 in “Frontiers in Plant Science” This study found that root hair growth is influenced by a complex interplay of auxin, inorganic phosphate, and transcription factors RSL2/RSL4, with reactive oxygen species playing a key role in this regulation.
11 citations
,
June 2017 in “Journal of cell science” In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.
4 citations
,
February 2021 in “Plant journal” This study found that the protein OsUEV1B is essential for maintaining phosphate balance in rice, with Pi deficiency leading to its inhibition and causing overaccumulation of phosphate in mutants.
2 citations
,
September 2022 in “Cellular and molecular biology” In this study, Agaricus bisporus derived β-Glucan particles demonstrated antimicrobial, antioxidant, and anticancer effects against cervical cancer HeLa cells, suggesting potential as a therapeutic option.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explored how root hairs integrate opposing growth signals but did not report new conclusive findings on the activation of known molecular players in polar growth.
15 citations
,
September 2018 in “Frontiers in Plant Science” This study identified that downregulation of the gene BcFLA1 decreases root hair length in Brassica carinata under phosphate-deficient conditions, highlighting its role in root hair elongation.
1 citations
,
December 2019 in “World rabbit science” This study found that high concentrations of supplemental cobalt inhibited hair follicle development in rabbits, potentially involving the mTOR-BMP signaling pathway.
18 citations
,
December 2016 in “Phytomedicine” In this study, applying 1% or 5% Curcuma aeruginosa essential oil lotion to the underarm for 10 weeks significantly slowed hair growth and brightened skin in young women, with no adverse effects reported.
June 2026 in “Dermatology and Therapy” This study reported that ritlecitinib was prescribed to a diverse group of patients with severe alopecia areata in the first 10 months after FDA approval, indicating its potential role in AA management.
2 citations
,
July 2021 in “Genes” This study identified a new genetic variant in the KRT71 gene responsible for a breed-specific form of hypotrichosis in Hereford cattle, potentially serving as a model for similar human conditions.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.
202 citations
,
August 2007 in “Biomaterials” This review discusses advancements in artificial skin for wound treatment and reports no new clinical findings; the authors highlight the potential of new biomaterials to enhance future skin replacement therapies.
196 citations
,
March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
40 citations
,
July 2015 in “Journal of Cellular Biochemistry” This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.
18 citations
,
February 2023 in “PLoS ONE” This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.
18 citations
,
July 2018 in “Turk Pediatri Arsivi-turkish Archives of Pediatrics” This study reported that the most common skin diseases among children in the Erzincan region of Turkey were preventable conditions, like acne and warts, suggesting the need for enhanced health education and preventive care.
18 citations
,
February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
11 citations
,
September 2020 in “Steroids” This study developed a new method using liquid chromatography-tandem mass spectrometry to measure multiple steroid hormones in hair, requiring significantly fewer strands than previous methods, with high accuracy and precision.
April 2026 in “Frontiers in Veterinary Science” This study observed that in privately owned, intact cats, male cats exhibited significantly higher long-term hair cortisol concentrations compared to females, while environmental and behavioral factors did not significantly impact cortisol levels, suggesting individual traits may influence stress markers more than external factors.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the use of cultured hair follicles for studying hair growth regulation and reports the challenge of modeling the entire hair cycle in vitro.
June 2024 in “Nature Cell and Science” In this research, experienced clinicians noted inconsistency in the reproducibility of the commonly used Hamilton-Ludwig scales for assessing pattern hair loss severity in photographic assessments, leading to the proposal of a new 5-point scale for staging female hair loss.
273 citations
,
May 2017 in “The Lancet” This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
1 citations
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August 2024 in “Zanco Journal of Medical Sciences” This study observed that women with PCOS have lower resistive and pulsatility index values in ovarian stromal arteries compared to normal women, indicating Doppler ultrasonography as an effective diagnostic tool for PCOS-related hemodynamic changes.
6 citations
,
June 2022 in “Journal of Clinical Medicine” This study found that for men with moderate-to-severe LUTS/BPH, 6 months of treatment with tamsulosin plus the hexanic extract of S. repens was as effective as tamsulosin plus a 5-alpha-reductase inhibitor but had better tolerability.