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This review highlights how integrating medicinal chemistry with delivery science could transform the limitations of PROTACs—such as poor solubility and low cell permeability—into strengths, potentially advancing these compounds from experimental stages to clinical applications by optimizing their delivery and enhancing therapeutic efficacy.

In this study, researchers developed and evaluated a herbal dual-action anti-dandruff shampoo, which demonstrated effective dandruff control, improved scalp health, and minimal irritation, making it a potentially safe and economical alternative to synthetic formulations for regular hair care.

This study evaluated a newly formulated herbal anti-dandruff shampoo containing natural ingredients such as neem and aloe vera, finding it effective and safe for dandruff control, with good cleansing, conditioning, and minimal irritation.

This study formulated an herbal hair dye using the medicinal herb Eclipta alba and other natural ingredients, finding it provided satisfactory coloring effects, conditioning benefits, stability, and safety, which supports its potential as a natural alternative to synthetic hair dyes.

This study evaluated a herbal hair oil formulated with medicinal plant-based ingredients, reporting its significant potential to promote hair growth, reduce hair fall and dandruff, and improve scalp health while maintaining stability and safety, suggesting it as a viable alternative to synthetic hair products.

This study formulated and evaluated a herbal hair oil combining coconut, olive, and other plant-based oils, finding it may promote hair growth, reduce hair fall, control dandruff, and improve scalp health, offering a stable, economical alternative to synthetic products.

This study investigated the pharmacognostic characteristics of Adenostemma lavenia leaves, identifying key diagnostic features and confirming the presence of major phytoconstituents such as alkaloids and flavonoids, to help standardize this traditional medicinal herb.

This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.

In this study, researchers developed a polyherbal antidandruff shampoo using medicinal plant extracts and found it exhibited significant antioxidant and antimicrobial properties, including activity against bacteria and fungi linked to scalp infections, suggesting it as a natural alternative to synthetic shampoos.

This study found that the polyherbal anti-dandruff shampoo formulated from medicinal plants like Azadirachta indica and Hibiscus rosa-sinensis demonstrated significant antioxidant and antimicrobial activities, including effects against dandruff-causing microorganisms, suggesting it could be a natural alternative to synthetic shampoos.

This review discusses the development and benefits of herbal hair dye formulations using medicinal plants like henna and indigo, noting their potential as safer, eco-friendly alternatives to synthetic dyes due to their nourishing and protective properties for hair and scalp.

This review concludes that herbal hair dyes made from medicinal plants like henna and indigo offer a promising natural alternative to synthetic hair colorants, potentially reducing side effects while providing additional benefits such as hair nourishment and scalp protection.

This study suggests that combining scalp cooling with resveratrol-loaded nanoparticles effectively protects hair follicles from chemotherapy-induced damage, highlighting a potential method to prevent hair loss during cancer treatment.

This study evaluated a herbal anti-dandruff hair wash powder, TRICHONEMTM, composed of eighteen herbal ingredients, reporting effective in vitro anti-dandruff activity and high user satisfaction in a 4-week pilot trial involving 50 women, without causing irritation.

In this study, researchers formulated a polyherbal hair oil using ingredients like coconut and castor oils, and reported that it boosts hair growth, reduces hair fall and dandruff, and adds shine, with minimal adverse effects compared to market formulations.

In this study, researchers developed poly herbal shampoo formulations using natural herbs like Ashwagandha and Amla, which showed effective hair care benefits including strengthening hair growth and preventing dandruff while maintaining safe pH and foaming capacity; however, stability studies for these formulations are needed.

This study developed a mask-cream containing Sabal palm extract and Sophora japonica tincture for androgenic alopecia prevention and treatment, establishing optimal production techniques using a reverse emulsion method.

This review reports that cerium oxide nanoparticles may accelerate wound healing in animal models, but further standardized and comparative studies are needed to confirm their potential for clinical applications.

This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.

In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.

This study found that encapsulating tamarillo polyphenols in cubosome nanoparticles protected them during digestion and enhanced the nutritional and antioxidant properties of yoghurt when used as a delivery system.

This review examines advancements in lipid and inorganic nanocarriers, such as liposomes and inorganic nanoparticles, for transdermal drug delivery, noting enhanced absorption and stability but acknowledging that few have reached clinical use.

This study found that male and female hair specimens show structural differences, with female hair having a brown color at the distal end and smooth surface texture, while male hair is completely black and shows surface irregularities; these differences may aid forensic analysis.

This study developed and tested a shampoo with semi-permanent dyes designed to gradually cover gray hair, reporting maintained stability and effective gray–black coloration on high-canities hair tresses through eight wash cycles.

In this review, researchers emphasized the importance of integrating natural extracts and modern cosmetic science to develop safe and effective hair-care products, highlighting herbal ingredients and modern advancements that enhance hair health and manageability.

This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.

This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.

In this study, researchers demonstrated that self-assembled gold nanoclusters with aptamers effectively deliver anti-NFκB aptamer drugs to inhibit hair follicle regeneration while being non-toxic to normal cells, offering a targeted treatment for hypertrichosis.

This study examined three olive oil formulations of baricitinib for topical delivery in treating alopecia areata, finding that Oil A showed the highest skin retention and maintained skin integrity without irritation, suggesting its potential for further investigation.

This study investigated the production of β-cyclodextrin from ginkgo seeds, finding that a pretreatment scheme involving high-temperature gelatinization significantly improved the conversion rate to 72.63%, highlighting the industrial potential of underutilized ginkgo seed powder for sustainable applications.