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3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Hair and nails can help diagnose diseases, with nail issues often linked to skin conditions and hair loss having various causes and treatments.

A new mutation in the Hairless gene causes hair loss in two Pakistani families.

The COVID-19 pandemic has increased hair loss and psychological distress in women.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Gellan gum hydrogels help recreate the environment needed for hair growth cell function.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

Platelet Rich Plasma-Derived Extracellular Vesicles show promise for healing and regeneration but need standardized methods for consistent results.

COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Not getting enough minerals can lead to health problems and shorter lifespans.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Topical prostaglandin E2 can help treat both alopecia areata and vitiligo.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Targeting colon cancer stem cells might lead to better treatment results.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.