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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.

Severe hair loss significantly worsens quality of life.

Not getting enough minerals can lead to health problems and shorter lifespans.

Androgenetic alopecia negatively affects quality of life, especially in younger, less educated, single, and rural individuals.

Human hair keratin might be good for filtering out harmful substances from water.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Zinc helps reduce the severity of depression.

The document suggests using safer, plant-based hair products instead of harmful synthetic ones.

The letter criticizes generalizations about older patients' abilities and calls for respectful, individualized care, while the original authors defend the need to adapt communication for those with impairments.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Higher androgen levels do not cause baldness in men.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

PCOS is linked to metabolic issues and infertility, needing more research.

Certain nutrients can improve skin health and treat skin problems safely.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Hair loss affects self-esteem and quality of life; treatments can help.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

Stress affects skin health and emotional well-being should be considered in skin disease treatment.

Maintaining sexual health after menopause is possible with patient approaches, hormone supplements, and therapy, despite needing more research.

People with facial disfigurements are judged more negatively, highlighting the social benefits of corrective surgery.

Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Many people with alopecia experience high levels of social anxiety, anxiety, and depression, and while wigs can boost confidence, they may also cause anxiety.