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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride may cause long-lasting sexual side effects.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Hair loss linked to higher heart disease risk in both men and women.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

Fatty acid transport protein 4 is essential for skin and hair development.

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.