5 citations
,
October 2020 in “Veterinary record case reports” In this case report, a 15-year-old golden retriever with calcinosis cutis showed accelerated improvement in FLE-treated skin infections compared to untreated areas, highlighting FLE's potential as a treatment adjunct.
128 citations
,
February 2016 in “British Journal of Dermatology” This study found that patients with alopecia areata experience significant impairments in health-related quality of life, notably affecting mental health, according to various quality of life assessment tools.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
78 citations
,
June 2022 in “Infection” Many COVID-19 survivors experience long-term symptoms like fatigue and sleep issues, needing ongoing medical support.
67 citations
,
March 2021 in “Dermatology and Therapy” This review discusses the substantial impact of alopecia areata on patients' health-related quality of life, highlighting issues such as personality changes, emotional and social difficulties, and a common occurrence of alexithymia, and emphasizes the need for more specific assessment tools.
1 citations
,
April 2024 in “Archives of disease in childhood” This systematic review found that among children and adolescents referred to specialist gender services, 36% received puberty suppression and 51% received masculinising or feminising hormones, but comprehensive data on psychological care and treatment pathways were lacking.
January 2026 in “Frontiers in Medicine” This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the significant psychosocial impact of alopecia areata on children and adolescents, affecting self-esteem, relationships, academic performance, and the well-being of their families.
January 2026 in “Dermatology Practical & Conceptual” In a systematic review and meta-analysis, the researchers found that intralesional triamcinolone acetonide was more effective than cryotherapy for achieving significant hair regrowth in patients with patchy alopecia areata, although both treatments had distinct safety profiles.
December 2021 in “Journal of Rheumatic Diseases” In this case report, a 13-year-old girl with pediatric systemic lupus erythematosus experienced rare ischemic vaso-occlusive retinopathy as a first symptom, and early interventions improved her visual acuity and fever but did not fully restore vision.
29 citations
,
January 2023 in “Journal of Clinical Medicine” This review discusses psychological treatments for alopecia, finding limited but positive effects on mental health, quality of life, and possibly hair growth; however, more research is needed to establish intervention efficacy.
28 citations
,
October 2018 in “Clinical Obstetrics and Gynecology” This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.
2 citations
,
February 2025 in “Medicine” This study found that among individuals with hair loss-related conditions, there was a significant association between alopecia and anxiety disorders, with affected individuals experiencing anxiety more frequently.
1 citations
,
April 2025 in “Journal of Clinical Medicine” This review reports that alopecia areata negatively affects sexual functioning, highlighting the need for further research due to limitations in current study sizes and populations.
July 2025 in “Biomolecules” This systematic review found that topical adenosine may increase hair thickness and density while reducing hair loss, but the strength of evidence is low due to issues with trial design and sample size.
February 2025 in “Healthcare” In this systematic review, the researchers observed that topical caffeine preparations appear safe and effective against hair loss, but most studies had low-quality evidence due to design flaws, indicating the need for better-designed trials before drawing definitive conclusions.
November 2024 in “Health Science Reports” This systematic review found that light and laser therapies, including excimer and erbium-glass lasers, generally increase hair density and diameter in various types of alopecia, with particularly notable effects in androgenic alopecia but limited efficacy in telogen effluvium.
50 citations
,
November 2020 in “Physiology & behavior” This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.
16 citations
,
October 2024 in “Journal of Paediatrics and Child Health” This systematic review highlighted significant psychosocial impacts of alopecia areata in children and adolescents, noting challenges such as reduced self-esteem, emotional distress, and social difficulties. The review underscored the need for further research to understand these effects comprehensively and guide clinical support.
15 citations
,
July 2022 in “Biomedicines” This study found no significant difference in the severity of alopecia areata between treatments with platelet-rich plasma and triamcinolone acetonide; further high-quality trials of PRP are needed.
6 citations
,
June 2022 in “Frontiers in Psychiatry” This review reported that anxiety, particularly generalized anxiety disorder, is common among patients with various medical illnesses, highlighting the need for its recognition and proper assessment in these settings.
4 citations
,
November 2022 in “Frontiers in Medicine” This study found that people with alopecia areata have a higher likelihood of experiencing anxiety and depression, and a moderate negative impact on their quality of life compared to healthy individuals.
January 2025 in “Journal of Pharmaceutical Research Science & Technology” This review explores the potential, challenges, and recent advancements of dissolving microneedles in drug delivery, summarizing their varied applications and current limitations without providing new clinical results.
November 2024 in “Applied Sciences” This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.
November 2022 in “Skin health and disease” This systematic review found a significant association between hair loss and mental health disorders such as major depressive disorder and anxiety, but it was unable to specify correlations for each type of hair loss.
January 2024 in “JEADV clinical practice” This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.
April 2024 in “Frontiers in medicine” This Delphi study found that moderate-to-severe alopecia areata in Poland, Czechia, Russia, and Türkiye significantly impacts quality of life and highlights an unmet need for more effective treatments.
32 citations
,
February 2008 in “Journal of the American Academy of Dermatology” This case report describes a family with autosomal dominant transmission of keratosis follicularis spinulosa decalvans, with observed treatment refractoriness in multiple topical and systemic therapies.
4 citations
,
January 2022 in “Yonsei Medical Journal” This article discusses the potential of novel microneedle transdermal systems for enhanced drug and vaccine delivery through the skin, but reports no clinical results and emphasizes ongoing trials.
3 citations
,
November 2018 in “PubMed” This study evaluated shaved style scalp medical tattoo (SMT) in individuals with advanced hair loss, reporting high patient and surgeon satisfaction scores.