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Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride negatively affects fish reproduction and gonadal development.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Wnt ligands are crucial for hair growth and repair.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Certain DNA variants can predict straight hair in Europeans but are not highly specific.

Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

M-CSF-stimulated myeloid cells can cause alopecia areata in mice.

Healthy scalp reduces hair loss by managing oxidative stress.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

The patient with total hair loss did not regrow hair despite treatment, indicating a poor outlook for this type of hair loss.

Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Finasteride, often used for hair loss, can potentially cause cataracts.

A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.