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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Maintaining anticoagulation is crucial for patients with antiphospholipid syndrome.

A woman with lupus had hair loss and skin issues that were successfully treated with medications.

Finasteride is effective for male hair loss, teledermatology is accurate and accepted, and cyclosporin helps treat toxic epidermal necrolysis.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

COVID-19 may trigger severe skin flare-ups in people with autoimmune conditions like lupus.

Using A132 hair dye with sunlight can cause skin damage and hair loss.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.

TTD hair brittleness is caused by multiple structural abnormalities.

Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Recognizing LET and AITD can help diagnose SLE early for better treatment.

Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.

A man with itchy skin lesions and weight loss was diagnosed with a rare skin condition linked to a pancreatic tumor.

The woman has Discoid Lupus Erythematosus and needs specialist care.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

New treatments like nanotechnology show promise in improving skin cancer therapy.

3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.

Blue light therapy is safe for skin and may protect against UV radiation.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Skin changes are key for early diagnosis and treatment of rheumatic diseases.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.