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This review explores the mechanisms by which UV radiation causes skin cancer, highlighting UV-induced DNA damage and its implications for cancer prevention strategies, but reports no new findings.

This study found that adipose‐derived stem cells can restore skin barrier function and inhibit photoaging-related responses in UVB-irradiated mice, suggesting a potential therapeutic role in managing skin photoaging.

This study found that overexpression of the enzyme ornithine decarboxylase in transgenic mice led to UVB-induced skin tumors, but this was prevented by the ODC inhibitor α-difluoromethylornithine.

Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.

This review compiles existing research on infrared radiation's effects on human skin, noting both its potential harmful thermal impacts and encouraging therapeutic applications, but reports no new clinical results.

This study highlights the roles of dietary nutrients in maintaining skin health, noting that shortages can lead to hard-to-detect dysfunctions, and suggests that nutraceuticals may help address these nutritional gaps and improve skin-related issues linked to aging and dermatoses.

This study found that combining red light therapy with oral beta-carotene significantly improved photoaging treatment outcomes compared to red light therapy alone, with Group A showing a 56.12% reduction in photoaging scores over 12 weeks versus 44.78% in Group B.

This review covers presentations from the 68th Annual Meeting of the Society of Investigative Dermatology and highlights research advances in dermatology, but reports no new clinical results.

This protocol details a method for inducing skin cancer in mice through chemical carcinogenesis, which studies cutaneous malignancies but does not report new findings.

This study found that overexpression of PKCepsilon in mouse epidermis was associated with increased susceptibility to metastatic squamous cell carcinoma, potentially through a mechanism involving tumor necrosis factor-alpha.

This article discusses a proposed "Darwinian" model of carcinogenesis and emphasizes that cancer prevention involves more than avoiding mutagens, as gene-environment interactions are complex and non-linear.

This study found that overexpression of PKCɛ in mouse epidermis increased sensitivity to metastatic squamous cell carcinoma, suggesting that a PKCɛ-mediated microenvironment may promote cancer development through specific cytokines like TNFα.

This study found that activating CXCR2 on ras-transformed keratinocytes promotes migration and tumor development in a mouse skin model.

This study found that low-dose topical alpha-terthienyl combined with UVA radiation can induce cutaneous photosensitization in guinea pigs, suggesting a possible photochemotherapy approach for skin diseases like psoriasis.

This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.

This review suggests that androgenetic alopecia may be exacerbated by exposure to ultraviolet radiation and proposes considering it as a photoaggravated condition requiring photoprotection.

This review discusses the genetic and environmental factors involved in the development of skin cancers like squamous cell carcinoma, basal cell carcinoma, and melanoma, but does not report new clinical findings.

This study found that topical alpha-terthienyl combined with UVA radiation rapidly induced dose-dependent cutaneous photosensitization in guinea pigs, suggesting potential for photochemotherapy in skin disorders without future carcinogenic risks.

This study found that acute UVB exposure in mice increases the synthesis of retinoic acid in the epidermis, which is necessary for normal repair from UVB light.

This study found that selectively inactivating ribonucleotide excision repair in mouse epidermis leads to DNA damage, keratinocyte intraepithelial neoplasia, and squamous cell carcinoma, indicating a potential tumor-promoting mechanism related to compromised genome maintenance.

This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.

This study found that facial sun damage scores from UV photography correlate with skin cancer and melanoma risk factors, suggesting this technology may help identify individuals at higher risk.

This study found that overexpression of ornithine decarboxylase and activated Ha-ras together led to a high rate of tumor development in a mouse model without additional carcinogens.

This article introduces a hypothesis that the enzyme catalase in processed meats may be a probable cause of higher cancer incidence due to its emission of electromagnetic fields, but no new clinical results are provided.

In this transgenic mouse study, preliminary findings suggest that overt melanocyte hyperplasia may require prior keratinocyte hyperplasia, indicating a potential role for keratinocyte mutation in early melanoma development.

In this study, targeting ornithine decarboxylase overexpression to hair follicle keratinocytes in mice was sufficient to promote skin tumor development without additional tumor promoters.

This case study in a renal transplant patient observed that eruptive KA-type SCCs exhibited aggressive behavior and genetic expression changes following intralesional chemotherapy, indicating potential caution against routine use of such treatments in similar cases.

This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in aging facial skin over 12 weeks.