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    Did you mean Phosphoinositide 3-kinase?
    Glossary Phosphoinositide 3-kinase

    enzyme involved in cell growth and survival signaling

    Phosphoinositide 3-kinase (PI3K) is an enzyme that plays a crucial role in cell growth, proliferation, and survival by activating signaling pathways inside cells. It is particularly important in the context of cancer research, as abnormal PI3K activity can lead to uncontrolled cell division and tumor growth.

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    Research 30 of 434

    1. Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia Dermatologic Surgery · 2019 · 11 citations
    2. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    3. PDGFA regulation of dermal adipocyte stem cells Stem cell investigation · 2017 · 3 citations
    4. Proteomic analysis of fetal skin by iTRAQ reveals molecular signals underlying Inner Mongolia Cashmere goat hair follicle initiation All Life · 2023 · 1 citations
    5. Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer Animals · 2023
    6. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020
    7. Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment Experimental and Therapeutic Medicine · 2019 · 7 citations
    8. Exploring the mechanism of Notopterygii rhizoma et radix in the treatment of psoriasis using a network Pharmacology approach and experimental validation Scientific Reports · 2025
    9. Phosphatidylinositol 3-Kinase/Akt-Dependent and -Independent Protection Against Apoptosis in Normal Human Melanocytes Journal of Investigative Dermatology · 2004 · 16 citations
    10. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    11. Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways Proceedings of the National Academy of Sciences of the United States of America · 2000 · 73 citations
    12. Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation Molecular therapy · 2014 · 13 citations
    13. Hétérogénéité tumorale du cancer de la prostate et infection par le SARS-CoV2 : une relation complexe impliquant les vésicules extracellulaires et le récepteur des androgènes SPIRE - Sciences Po Institutional REpository · 2023
    14. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006 · 9 citations
    15. Ginsenoside Rb1 promotes the growth of mink hair follicle via PI3K/AKT/GSK-3β signaling pathway Life Sciences · 2019 · 28 citations
    16. Ginsenoside Rg4 Enhances the Inductive Effects of Human Dermal Papilla Spheres on Hair Growth Via the AKT/GSK-3β/β-Catenin Signaling Pathway Journal of Microbiology and Biotechnology · 2021 · 4 citations
    17. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    18. Caizhixuan hair tonic regulates both apoptosis and the PI3K/Akt pathway to treat androgenetic alopecia PLOS ONE · 2023
    19. Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique NPJ breast cancer · 2024 · 1 citations
    20. Anti-Hair Loss Effect of Adenosine Is Exerted by cAMP Mediated Wnt/β-Catenin Pathway Stimulation via Modulation of Gsk3β Activity in Cultured Human Dermal Papilla Cells Molecules · 2022
    21. Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells Clinical and Experimental Dermatology · 2017 · 22 citations
    22. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    23. Enhancement of Hair Growth through Stimulation of Dermal Papilla Cells in Human Follicular Dermal Open access journal of pharmaceutical research · 2018
    24. Optimizing clinical monitoring and management guidelines for capivasertib in HR-positive/HER2-negative advanced breast cancer: expert opinion npj Breast Cancer · 2025
    25. Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway Indian Dermatology Online Journal · 2023
    26. The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis International Journal of Molecular Sciences · 2018 · 177 citations
    27. Enzymes British Journal of Pharmacology · 2008
    28. Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients Archives of Gynecology and Obstetrics · 2017 · 24 citations
    29. ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change Journal of experimental botany · 2013 · 161 citations
    30. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018 · 18 citations