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    Research 421–450 of 770

    1. First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors Journal of clinical oncology · 2011 · 505 citations
    2. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011 · 499 citations
    3. Folliculin encoded by the <i>BHD</i> gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proceedings of the National Academy of Sciences · 2006 · 475 citations
    4. NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008 · 415 citations
    5. The complex relationship between TFEB transcription factor phosphorylation and subcellular localization EMBO journal · 2018 · 344 citations
    6. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    7. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011 · 283 citations
    8. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013 · 277 citations
    9. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer 2013 · 224 citations
    10. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations
    11. The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors Drug Metabolism Reviews · 2006 · 219 citations
    12. Lactate dehydrogenase activity drives hair follicle stem cell activation Nature cell biology · 2017 · 202 citations
    13. Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011 · 191 citations
    14. Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective International Journal of Molecular Sciences · 2023 · 188 citations
    15. BRAF Inhibitor Dabrafenib in Patients with Metastatic <i>BRAF</i>-Mutant Thyroid Cancer Thyroid · 2014 · 188 citations
    16. Chemistry42: An AI-Driven Platform for Molecular Design and Optimization Journal of Chemical Information and Modeling · 2023 · 180 citations
    17. Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation Proceedings of the National Academy of Sciences · 2013 · 176 citations
    18. Pharmacologic inhibition of JAK-STAT signaling promotes hair growth Science Advances · 2015 · 159 citations
    19. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    20. Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop Genes & Development · 2012 · 138 citations
    21. Tregs: Where We Are and What Comes Next? Frontiers in Immunology · 2017 · 130 citations
    22. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    23. VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK Experimental Cell Research · 2012 · 120 citations
    24. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    25. Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 116 citations
    26. PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery Journal of Chemical Information and Modeling · 2024 · 110 citations
    27. The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth 2018 · 109 citations
    28. A Receptor-Like Kinase Mediates Ammonium Homeostasis and Is Important for the Polar Growth of Root Hairs in<i>Arabidopsis</i> ˜The œPlant cell · 2014 · 107 citations
    29. Copper−Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity Molecular Pharmaceutics · 2010 · 102 citations
    30. Pulmonary manifestations of Birt-Hogg-Dubé syndrome Familial cancer · 2013 · 99 citations