23 citations,
January 2014 in “Molecular Therapy” Applying a special DNA plasmid to the skin can make it thicker and stronger.
22 citations,
July 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
505 citations,
December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
92 citations,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
29 citations,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
37 citations,
March 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
31 citations,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
10 citations,
October 2021 in “Animal nutrition” Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.
99 citations,
May 2013 in “Familial cancer” People with Birt-Hogg-Dubé syndrome often have lung problems and delayed diagnosis, and better recognition of CT scan signs could improve diagnosis and management.
5 citations,
September 2022 in “Research Square (Research Square)” CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
February 2023 in “Research Square (Research Square)” Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
29 citations,
March 2014 in “PloS one” Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.
293 citations,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
247 citations,
August 2011 in “European Journal of Epidemiology” The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
July 2018 in “Elsevier eBooks” Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.
January 2023 in “Annals of dermatology/Annals of Dermatology” A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
5 citations,
February 2014 in “Journal of chemical ecology” Eastern Red Bat hair contains various glycerophospholipids, mainly phosphatidylcholine.
48 citations,
September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
24 citations,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
1 citations,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.
22 citations,
December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
16 citations,
July 2020 in “International Journal of Molecular Sciences” Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.
January 2012 in “Else Kröner-Fresenius Symposia” Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
August 2024 in “Cosmetics” Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.
166 citations,
November 1990 in “Journal of Investigative Dermatology” Minoxidil sulfate stimulates hair growth.
14 citations,
January 2016 in “Biochemical and Biophysical Research Communications” Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.
7 citations,
March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
1 citations,
February 2024 in “Pharmaceutics” Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.
October 2024 in “International Journal of Molecular Sciences” Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.