research Design, Synthesis and Anti-Tumor Evaluation of Novel Thiohydantoin Congeners as Androgen Receptor Antagonists With In Vivo Study
A new compound, 3a, effectively fights prostate cancer better than finasteride.
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research (1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research Novel Cosmeceuticals from Plants: An Industry-Guided Review
Plant-based ingredients are effective and safe for modern skincare products.
research Cutaneous Latanoprost in the Treatment of Alopecia Areata
Applying latanoprost on skin can stimulate hair growth with minimal side effects.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research The 3D Bioprinted Scaffolds for Wound Healing
3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research An Efficient Synthesis of Dutasteride: Utilizing Benzoyl Group as Novel Lactamic Protecting Group
Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Hypertrichosis of the Eyelashes Caused by Bimatoprost
Bimatoprost can cause excessive eyelash growth.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Enzyme-Linked Immunosorbent Assays for Doping Control of 5α-Reductase Inhibitors Finasteride and Dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates
Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
research Hypertrichosis of the Malar Areas and Poliosis of the Eyelashes Caused by Latanoprost
Latanoprost eye drops caused excessive cheek hair growth and eyelash whitening in a woman.
research Potential of Nano-Phytochemicals in Cervical Cancer Therapy
Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
research Recent Progress in Prostaglandin F2α Ethanolamide (Prostamide F2α) Research and Therapeutics
New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.
research Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss
Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.
research Sulfation of Minoxidil by Human Platelet Sulfotransferase
Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
research Contact Dermatitis to Minoxidil
Minoxidil can cause skin irritation like eczema and rash in some users.
research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Hair Amino Acids: Normal Values and Results in Metabolic Errors
Hair amino acid levels can indicate metabolic disorders.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Acute and 30-Day Oral Toxicity Studies of a Novel Coccidiostat – Ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research Hypertrichosis of the Malar Areas and Poliosis of the Eyelashes Caused by Latanoprost
Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.