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More East Asians are accepting and getting facial plastic surgery, with a focus on natural-looking results and using both surgical and nonsurgical methods.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

The UK's EDS National Diagnostic Service found that early diagnosis, lifestyle advice, and regular check-ups are crucial for managing vascular Ehlers-Danlos syndrome. A combination of losartan and bisoprolol can reduce vascular events, improving survival and quality of life.

Forensic DNA Phenotyping accurately predicts physical traits and is used in investigations, but needs more diverse population data for confirmation.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.

Lab-grown nail cells show characteristics similar to natural nail and hair.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

PCOS may have evolved as an advantage in past environments with food scarcity.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Hormones and genes affect hair growth and male baldness.

People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.

Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

More research with diverse participants is needed to determine the effectiveness of photobiomodulation devices for hair loss treatment.

Moles on the scalp are more common in people with more body moles and atypical moles, but not linked to balding.

Finding a positive nonsentinel lymph node in melanoma patients indicates a worse prognosis.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.