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Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

AMH is a good marker for diagnosing PCOS, but global standards are needed.

Researchers developed a cost-effective 66 K SNP chip for cashmere goats that is accurate and useful for genetic studies.

Genomic approach finds new possible treatments for hair loss.

Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

About 5% of Thai university girls aged 17-19 have polycystic ovary syndrome, with moderate acne being a strong risk factor.

Some skin diseases and their treatments can negatively affect male fertility.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

Various treatments exist for hair loss, but more research is needed for better options.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

New technologies help us better understand how skin microbes affect skin diseases.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.