45 citations,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
30 citations,
March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
19 citations,
April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
13 citations,
November 2019 in “Scientific reports” Certain drugs change freshwater snail shells to a "banana" shape.
11 citations,
August 2019 in “The Journal of Sexual Medicine” Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.
6 citations,
May 2006 in “Skinmed” Androgens contribute to common male hair loss; more research needed for hair growth medication.
5 citations,
June 2021 in “Pharmacological Reports” Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
4 citations,
November 2016 in “Pediatric Clinics of North America” The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
November 2018 in “International Journal of Current Pharmaceutical Research” PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
January 2016 in “Georg Thieme Verlag eBooks” More East Asians are accepting and getting facial plastic surgery, with a focus on natural-looking results and using both surgical and nonsurgical methods.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
773 citations,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
237 citations,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
157 citations,
October 2003 in “Development” AXR3 and SHY2 genes control the growth and timing of root hair development in plants.
151 citations,
December 2004 in “Annals of the New York Academy of Sciences” Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
137 citations,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
49 citations,
January 2010 in “International Journal of Pediatric Endocrinology” The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
42 citations,
August 2017 in “Human Reproduction” Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
38 citations,
December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
37 citations,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
31 citations,
November 2014 in “Journal of Endocrinological Investigation” Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
29 citations,
February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
28 citations,
March 2007 in “Journal of The European Academy of Dermatology and Venereology” At least 87% of Indian men experience hair loss, with type II being most common and severity increasing with age.
26 citations,
December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
20 citations,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
18 citations,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.