research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
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research Ligand-Independent Regulation of the Hairless Promoter by Vitamin D Receptor
Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Assessment of Diagnostic Competence of Plasmatic Androgens on Polycystic Ovary Syndrome Based on Receiver Operator Characteristic Curves
Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
research Alopecia: Association with Resistance to Thyroid Hormones
A specific thyroid hormone resistance mutation may be linked to different types of hair loss.
research Caspases in Life and Death: Their Role in Head Formation
Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
research Siberian Cats Help in Solving Part of the Mystery Surrounding Golden Cats
The CORIN gene variant causes the golden color in Siberian cats.
research The Value of the Free Androgen Index Depends on the Phenotype of Polycystic Ovary Syndrome: A Single-Centre Experience
The free androgen index varies among women with different types of PCOS.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research Triglycerides, Independent of Ferriman Gallwey Score, Is a Main Determinant of Free Testosterone Index in PCOS
High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
research Genetic Correlation Analysis Does Not Associate Male Pattern Baldness With COVID-19
There's no significant genetic link between male pattern baldness and COVID-19.
research Cardiovascular Disease Risk in Women with Hyperandrogenism, Oligomenorrhea, or Polycystic Ovaries: A Systematic Review and Meta-Analysis
Women with irregular periods have a higher risk of heart disease.
research Five Cluster Classifications of Long COVID and Their Background Factors: A Cross-Sectional Study in Japan
The study identified five types of long COVID symptoms and suggests tailored management strategies for each.
research Aging Skin and Non-Surgical Procedures: A Basic Science Overview
Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
research Analysis Of The Function Of ADAM17 In IRhom2 Curly-Bare And Tylosis With Esophageal Cancer Mutant Mice
Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
research Development and Evaluation of Novel Rodent Model of PCOS Mimicking Clinical Phenotype in Human Disease
The new rodent model successfully mimics non-lean human PCOS symptoms.
research A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia
A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.
research Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation
Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
research Rotterdam Criteria–Based Diagnostic Subtype Is Not a Strong Predictor of Cutaneous Phenotype in Patients With Polycystic Ovary Syndrome: A Cross-Sectional Study
The type of PCOS a woman has doesn't strongly predict her skin or metabolic symptoms; obesity is a more important factor.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research No Increased Risk of Alopecia in Ankylosing Spondylitis Patients: A Population-Based Cohort Study in Taiwan
People with ankylosing spondylitis in Taiwan don't have a higher chance of getting alopecia.
research Efficient Editing of CSLD2 Orthologue by CRISPR/Cas9 Affects Cell Morphogenesis of Root Hair in Spinach
CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.
research An Indian Evidence-Based Study of Prevalence, Phenotypic Features, and Lifestyle Modifications of Polycystic Ovarian Syndrome Patients
The study found that PCOS affects about 6.5-6.8% of women in both urban and rural areas of Telangana, India, and highlighted the importance of lifestyle changes for management.
research Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus
Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.
research Advances in the Genetic Understanding of Hypohidrotic Ectodermal Dysplasia
Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Cell Kinetics of the Human Hair Follicle
The document concludes that understanding how cells in the hair follicle grow and change is important for regulating hair growth.
research Comprehensive Management of Polycystic Ovary Syndrome: The Role of Metformin in Addressing Metabolic and Endocrine Dysregulation
Metformin helps manage PCOS by improving metabolism and ovulation, but should be part of a personalized treatment plan.
research Functional Evaluation of Novel CYP21A2 Variants: Expanding the Genetic Basis of Non-Classic CAH
Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
research Functional Evaluation of Novel CYP21A2 Variants: Expanding the Genetic Basis of Non-Classic Congenital Adrenal Hyperplasia
Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.