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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Transplant patients often get skin problems, with treatments varying by condition.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.

Finasteride for hair loss lowers PSA levels, so PSA values need adjusting when screening for prostate cancer.

Dutasteride 0.5mg improves hair growth in 78% of people with hair loss, but may cause sexual problems in some.

Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.

Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Targeted cancer therapies often cause serious skin problems that need careful management.

New effective scar treatments are urgently needed due to the current options' limited success.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Laser device increases hair density, safe for treating hair loss in men and women.

Use minoxidil for hair loss treatment; assess results after 6 months.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.