research A Phase I Study of Topical Tempol for the Prevention of Alopecia Induced by Whole Brain Radiotherapy
Tempol is safe and may prevent hair loss from brain radiotherapy.
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research Phase I/IIa Clinical Trial for the Treatment of Androgenetic Alopecia Using Intradermal Injections of Cultured Autologous Dermal Sheath Cup Cells
Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research Estradiol Protects Hair Cells From Cisplatin-Induced Ototoxicity Via Nrf2 Activation
Estradiol may protect ear cells from hearing loss caused by a chemotherapy drug by activating a protective pathway.
research Protective Activity Against Oxidative Stress in Dermal Papillae With Extracted Herbal Essential Oils
Lavender, lemongrass, rosemary, and chamomile essential oils may help protect cells important for hair growth from damage and could promote hair growth.
research Quality of Life of Patients with Metastatic Breast Cancer Treated with Epirubicin and Docetaxel
Patients with metastatic breast cancer treated with epirubicin and docetaxel had a good response and maintained their quality of life.
research Frozen Glove Therapy for Docetaxel-Induced Hand Problems May Not Fit All
Wearing a frozen glove during chemotherapy can reduce nail and skin problems but may not be comfortable for everyone.
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Comparison of Glutathione S-Transferase and Cytochrome P-450 IA1 Activities in Cultured Keratinocytes and Reconstructed Epidermal Models
Reconstructed skin models are useful for studying how skin processes certain chemicals.
research Profile Analysis of Adverse Events After Boron Neutron Capture Therapy for Head and Neck Cancer: A Sub-Analysis of the JHN002 Study
Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.
research Racial and Ethnic Disparities in Androgenetic Alopecia Clinical Trials in the United States
Androgenetic alopecia trials in the U.S. lack racial and ethnic diversity, limiting their applicability.
research Alopecia in Patients Treated with Molecularly Targeted Anticancer Therapies
Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
research Hidradenitis Suppurativa Secondary to Treatment With a Gamma Secretase Inhibitor
A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.
research Aqueous Extract of Mentha Suaveolens Induces Nrf-2 Activation and Expression of Antioxidant and Detoxifying Enzymes in Human Keratinocyte HaCaT
Mint water extract boosts protective enzymes in skin cells.
research Incidence of Alopecia from Endocrine Therapies in Cancer
Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.
research Efficacy and Safety of Docetaxel in the Elderly
Docetaxel is safe and works well for older people with cancer, with manageable side effects.
research Kinase Inhibition with BAY 43-9006 in Renal Cell Carcinoma
BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.
research New Agents for Cancer Chemoprevention
Over 30 potential cancer prevention treatments are being tested, with some showing promise in early research.
research Liposomes in Cancer Therapy
Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
research Docetaxel
Docetaxel is effective against various cancers but mainly causes neutropenia.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Anthracycline Analogs: The Past, Present, And Future
Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata
A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Prodrugs of Butyric Acid from Bench to Bedside: Synthetic Design, Mechanisms of Action, and Clinical Applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Treatment of Chemotherapy-Induced Alopecia
Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
research Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration
Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.