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Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Daily low-dose aspirin lowers minoxidil's effectiveness for hair loss treatment.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Topical booster improves hair loss treatment effectiveness.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

The combination treatment showed a higher response rate but no significant survival benefits.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.

Mice with human gene experienced hair loss when treated with DHT.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Finasteride helps hair growth but may cause sexual side effects and depression.