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Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.

Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.

The document concludes that various treatments for skin conditions are effective, but some require further research, and certain factors like gender and lifestyle can influence disease outcomes.

Phospholipase A2 enzymes play key roles in skin health and disease.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

Certain types of mucopolysaccharidoses cause significant hair abnormalities.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.

Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride effectively treats male hair loss, improving growth and density.