research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
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research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Metformin: An Old Medication of New Fashion: Evolving New Molecular Mechanisms and Clinical Implications in Polycystic Ovary Syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Adverse Effects of Opioid Analgesic Drugs
Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
research ATP-Competitive mTOR Kinase Inhibitors Delay Plant Growth by Triggering Early Differentiation of Meristematic Cells Without Developmental Patterning Change
Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Physiological and Retinoid-Induced Proliferations of Epidermis Basal Keratinocytes Are Differently Controlled
Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
research A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A
Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
research External Genitalia Abnormalities in Male Rats Exposed In Utero to Finasteride, a 5α-Reductase Inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research Potassium Channel Therapeutics at the Bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
research Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial
Spironolactone most effective for hirsutism, but has side effects.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in the Arabidopsis Root
Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.
research Minoxidil Versus Nitroglycerin: A Prospective Double-Blind Controlled Trial in Transcutaneous Erection Facilitation for Organic Impotence
Minoxidil works better than nitroglycerin for treating impotence with fewer side effects.
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
research T Helper 17 Cell/Regulatory T-Cell Imbalance in Hidradenitis Suppurativa/Acne Inversa: The Link to Hair Follicle Dissection, Obesity, Smoking, and Autoimmune Comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
research Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice
Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.